Streptococcal bacteriophage in the nose. 'Streptococcal bacteriophage'. Method and features of application

2016-08-22 00:01:41

Roman asks:

Good afternoon, after long-term treatment of vesiculitis with antibiotics 02.16-03.16 months (orcipol, levofloxacin, summamed), dysbacteriosis manifested itself, drank probiotics for three months (bifidubacturim, linex, ..) and a diet, there were still two courses of makmimor for 5 days 05-06.2016 month.

for today we have:
1) chronic pharyngitis-tonsilitis with granules on the back wall (the throat does not hurt, it persists, and was already half a year before vesiculitis), tonsil swab 08.2016 - Streptococcus pyogenes 10 ^ 6 CFU (Intestaphage sextaphage is resistant, all antibiotics are sensitive)
2) the analysis for toxacarosis - weakly positive as of 04.2016, the course of aldazole 10 days - after the analysis for toxocara antibodies showed a positive result (5 times higher than the norm of toxocara antibodies on 6.2016 month and 7 times higher than the norm on 8.2016 month)
3) chronic urethritis-prostatitis - prostate secret - Pseudomonas aeruginosa 10 ^ 5 CFU, microflora - abundantly coccal
(sextaphage intestiphage - sensitive, pseudomonas bacteriophage - insensitive, Amoxiclav -, azithromecin +, gentamicin +, doxycycline-, cefotaxime +, cefepime +, ceftriaxone -, levofloxacin +)

viruses were not detected, bacterial culture of feces (Escherichia coli 10x7, lactobacilli
- in (1) case, the doctor proposes treatment with staphylococcal toxoid for 5 days and topically sixth bacteriophage with washing of the tonsils, taking IPS19 and instilling the bacteriophage did not give a tangible improvement in 12 days, how dangerous the use of the vaccine is for immunity, given that there is a streptococcal infection and not staphylococcal?
- in (2) variant, another infectious disease specialist suggests drinking another aldazole twice for 10 days with a break, is it worth taking the course?
- in (3) case, a homemade vaccine with strains of pseudomonas, enterobacter, streptococcus and other bacteria is offered, how dangerous is a homemade auto vaccine?

Answers Vazquez Estuardo Eduardovich:

Hello Roman! I did not find a question in your appeal, and yet: due to a violation of the intestinal microflora, immunity was suppressed, against the background of some chronic inflammation. Consult a local therapist, and he will give the necessary recommendations depending on the clinic and the need for today.

2015-04-27 11:43:42

Maria asks:

Hello! for half a year already torments hr. tonsillitis and, as a result, lymphadenitis. the throat does not hurt in practice, the tonsils are not greatly enlarged, although there are plugs, the inflamed lymph nodes in the neck and submandibulars torment. Laura did not want to take smears from me, I had to go to the laboratory myself and take it. as a result, it turned out that a-hemolytic streptococcus (10 to the 7th degree at a rate of 10 to 5 -10 to 6th), neisseria spp 10 to the 7th degree at the same rate as in the previous one and Staphylococcus aureus 5x10 in the 4th, and in the norm should not be written at all. respectively, the sensitivity of all three to antibiotics amoxycycline, gentamicin, doxycycline, ciprofloxacin, and Staphylococcus aureus sensitivity to staphylococcal, intestinal, polyvalent and complex bacteriophages. Lore reluctantly prescribed doxycycline for 10 days. and I am afraid, because I have dysbiosis, but I got lymphadenitis, I get a little cold - everything immediately becomes inflamed and aching .. I will also note that at the very beginning of treatment I was prescribed a staphylococcal bacteriophage blindly without a smear, I did not feel any improvement from it. Please advise how to be?

Answers Vadim Kotsarenko:

Good afternoon, Consultations of a therapist, ENT (change doctor) are shown. It is possible to consult an immunologist, but not a fact. The therapist will decide. In the complex of treatment, in addition to drug therapy, physical. procedures (laser, quartz tube).

2015-02-20 13:09:11

Gulnara asks:

Hello! Passed tests (bacterial culture) from the pharynx and revealed Streptococcus pneumoniae with abundant growth of 3 degrees. the analysis was handed over after treatment with antibiotics. Is there any bacteriophage treatment possible? antibiotics are now prescribed again.

2014-11-17 10:24:34

Arimas asks:

Good day!
It all started with the tongue, itched when taking nuts, took a look and found on the Internet the concept of a geographical language. Spiral turntables change shape every day. Sprinkled a month with nystatin, not passed. I handed over the bacteriophage on the tongue, the tests showed a large number of streptococci and staphylococci, the doctor prescribed bacteriophages - 20 ampoules of oral administration and one antibiotic, sorry I do not remember the name. After taking it, I felt improvements in the body, but on the tongue, as it was, those turntables continue to turn. But even more that I noticed when there is stress or the height of emotions, the language literally shakes.
Here's what to do next, tell me, I'm tired of the fact that all the time the tongue is tearing something, it seems to heal, but then a white spot reappears, which grows and has been there for half a year. How can this be cured?

Answers Imshenetskaya Maria Leonidovna:

Good afternoon. There are many reasons for the geographic language and are often not treated. Contact the center for the treatment and prevention of diseases of the oral mucosa, where you will have all the necessary tests. diagnose and prescribe treatment. Good luck to you

2014-08-02 11:13:29

Alla asks:

Hello, help me figure out the treatment !!! 1.5 months ago, for no reason at all, tenosynoveitis of the wrist joint began. Discovered neuropathy on 2 sides of the nerves in the arms. Examined with a rheumatologist, all tests are negative (blood is normal, cfr, rheum factor, ena screening is negative). For a month now, my hands and knees have been aching, low-grade fever, sweating at night. I passed a throat swab and found streptococcus and staphylococcus. In the blood, the Epstein Barra virus-vca-igG-2.9 (critical up to 0.155), vca-igm-negative. Ea-igG-neg. Na-igG-2.86 (critical up to 0.160). She took bacteriophages and amoxicillin. On the background of amoxicillin, mild tonsillitis began. The immunologist prescribed Epstein-Barr virus immunoglobulin 3 ml every 3 days 10 times. And nothing more! Tell me what to do ?! After 3 days, go on vacation to the sea, and the symptoms persist!

Answers Shidlovsky Igor Valerievich:

Well, the symptoms are not life-threatening, so you can safely go to the sea. Then I advise you to do an x-ray of the lungs, ultrasound of the abdominal organs, liver function tests, tests for viral hepatitis B and C, HIV infection, syphilis, urine and blood cultures for sterility. There is nothing more to say in absentia.

2014-06-04 13:41:31

Irins asks:

Hello dear doctor ... I really need your advice ...

I am 20 years old .... after antibiotic treatment for sinusitis, I developed intestinal dysbiosis and severely weakened my immunity. Namely:
Was tested for intestinal dysbiosis:
Hemolytic Escherichia coli: 100%,
candid 10 to 5 degrees
I took a swab from the nose:
We discovered Staphylococcus aureus 5 * 10 to the 3rd degree; (I have light green crusts in my nose, like nothing else torments me).
passed a swab from the throat:
found a small amount of candida, and in-streptococcus hemolytic (not group A) 10 to 4 degrees; (my mouth is severely inflamed-glossitis, the ENT doctor did not see any indications for prescribing an antibiotic, there are no sore throats, etc. );

I passed a swab from the eye to the tank, sowed, sowed streptococcus viridans 10 to 3 degrees (after using the antibiotic, I started to have conjunctivitis-sluggish, the eye doctor said that streptococcus cannot cause conjunctivitis, and the fact that my immunity was simply weakened and prescribed to drip zinc drops in the eyes, another doctor prescribed a drip of chloramphenicol and insists on it.).

I handed over a tank of urine, sowed Klebsiella pneumonia 10 to 6 degrees. Sometimes I have pains in the bladder and white crumbs in my urine ... but mostly the urine is good ...

Doctor please tell me:
1.Is it necessary to treat streptococcus viridans in the eye? and can it cause conjunctivitis?
2. Is it necessary to treat hemolytic streptococcus in the throat with what exactly?

3.Is it necessary to treat staphylococcus aureus in the nose?

4.Is it necessary to treat and how to treat Klebsiella pneumonia in urine? and how could she get there? I have never lived and never live sexually, doctors prescribe antibiotics for Klebsiella, tell me how much you can take a bacteriophage Klebsiliosis pneumonia - to completely recover from Klebsiella?

At the moment I am taking Irunin for the treatment of thrush, I am very afraid to take antibiotics ..... after cefazolin, my immunity is very strong ...

Answers Sukhov Yuri Alexandrovich:

Hello Irins.
Yes, not easy, I agree.
I always do not forget to repeat to doctors at lectures that "it is necessary to treat not a disease, but a patient!"
In your case, this is just a textbook example. You need a good doctor who can work in collaboration with an ophthalmologist, ENT, immunologist and other specialists.
I am sure that everything will be fine, but it will take time, money and effort. You cannot take any immunomodulators (except phytopreparations - adaptogens) without examining your immune system and consulting. You, as a patient, need a comprehensive, balanced approach !!
Recover! Everything will be fine!
From SW., Yu Sukhov.

2014-04-04 22:23:25

Nadezhda asks:

Hello, this is probably a cry from the heart ... My problem is that I have permanent plugs in my right mendaline, they are not large, it seems to me for chronic tonsillitis, small, but they have a couple of deep dimples, where I noticed and food gets also, in addition to the constant life of traffic jams there, in my throat I feel a terribly unpleasant odor-smack, these sensations are hard to describe .. always there something comes out ... Candida, Staphylococcus aureus in the 3rd degree and alpha hemolytic streptococcus were identified in the inoculation from the pharynx. I took the tests a year ago and since then I went to a bunch of doctors and received various advice before removing them and the answer that I had nothing to remove there and suck decatilen. In fact, I was not treated with antibiotics, I am resistant to all penicillins, and to what I am not resistant, I have heard little that resistance arises quickly and it is not a fact that after treatment with strong antibiotics there will be a result, and I am afraid to drink them because I have gastritis and a weak pancreas , as they say, we treat the other we cripple. Also, I have been drinking lindinet 20 for 2.5 years and for women's health I cannot refuse them, and I also heard that hormonal tablets shake immunity. My question to you is, how do you treat me from this, is there a bacteriophage method for me very expensive, maybe there is something simpler that kills this muck, and also for many years my normal temperature is 37.2, I just don't feel it just like without changing She's like that, I'm 27, I haven't given birth yet and I'm afraid of the complications I read about the joints and the heart. The throat, in the presence of pus and plugs, does not hurt, but once a year I can get sore throat with fever

Answers Shidlovsky Igor Valerievich:

Have you cleaned your tonsils (it hurts with a spatula to expand the grooves in the tonsils)? 2. Antibiotics are strictly necessary! Pick up by sowing, you can use the old way. 3. Conduct non-specific and specific immunotherapy.
It is impossible to treat in absentia and on an Internet. If anything - contact the appointment.

2014-02-06 17:14:50

Olga, 24 years old asks:

Hello. Disturbed by frequent colds (about 5 per year), periodically sore throat with redness of the back wall. Diagnosis of chronic tonsillitis. There are no sore throats, there is no high temperature, the plugs are not visible, on the third rinsing everything is clean, the tonsils are not large. The temperature of 36.9-37.2 is kept for about a year. It rises during the day, mainly at lunchtime, very rarely in the morning.
Was examined
1. General blood test, for about two years ESR is increased from 20 to 35, at a rate of no more than 15. Sometimes leukocytes are slightly increased (10 at a rate of up to 9)
2. Biochemistry is normal.
Rheumatoid factor is normal
C-reactive protein norm
ASLO up to 500 at a rate of 0.01-200
A decrease to 200 was observed with complex treatment (washing of the tonsils, rinsing, antibiotics, bacteriophages), then an increase again.
3. Blood sterility rate
4. Antibodies to antigens of opisthorchis, echinococcus, toxocar, trichinella IgG negative
5. Antibodies to cytomegalovirus IgG positive (93.8)
(indicators less than 0.5 negative
more than 1.0 positive)
6.Antibodies to cytomegalovirus IgM negative
7.Antibodies to the nuclear antigen of the Epstein-barr virus IgG positive (32.10) (indicators less than 5 negative; more than 20 positive); Antibodies to the capsid protein of the Epstein virus barr IgM are negative.
8. PCR diagnostics
DNA from candida albicans, chlamydia pneumonia, streptococcus pneumonia, mycoplasma pneumonia, streptococcus pyogenes was not found in the scraping.
9. Smear from the throat, detected staphylococcus aures 1 * 10 to 5 degrees
10. Antibodies to toxoplasmosis IgG and IgM negative
11. hormones Tz, T4 free, TSH sensitive rate
12.Immunoglobulins G, M, E norm
13.Analysis of urine, general and according to Nechiporenko, the norm
14 Cala Analysis Norm
15. Ultrasound of the abdominal cavity, kidneys, thyroid gland, lymph nodes, mammary glands is normal
16. ECHO of the heart is normal, ECG is a moderate change in the myocardium
17. CT scan of the chest without pathology
18. Consultations of a gynecologist, cardiologist, dentist, infectious disease specialist, rheumatologist, endocrinologist are all normal.
TELL! QUESTION
* Is there a test to determine the function of the tonsils?
* One doctor suggests removing tonsils, based on the indications of ASLO, others advise to wait, treat.
* Long-term temperature is typical for tonsillitis? * Could it be associated with lowered immunity?
WHAT MORE Surveys would you recommend?

One bottle of Streptococcal Bacteriophage can contain 20 or 100 ml of sterile phagolysate streptococcal strains.

The additional substance is 8-hydroxyquinoline sulfate monohydrate.

Release form

Yellow transparent solution:

  • 20 ml solution in a bottle - four or ten bottles in a cardboard box.
  • 100 ml solution in a bottle - one bottle in a cardboard box.

pharmachologic effect

Antibacterial specific action.

Pharmacodynamics and pharmacokinetics

Streptococcal bacteriophage - a virus that causes selective destruction of bacteria of the genus Streptococcus and does not affect human cells.

The features of pharmacokinetics have not been studied.

Indications for use

Therapy and prevention of diseases caused by strains of the genus Streptococcus as part of multicomponent therapy:

  • lesions of the digestive tract ( , gastroenterocolitis, );
  • diseases of newborns of a purulent-inflammatory nature ( gastroenterocolitis, pyoderma, sepsis, conjunctivitis );
  • surgical diseases ( hydradenitis, suppuration of wounds, , felon, phlegmon, boils, burns, , );
  • urogenital infections ( , salpingo-oophoritis );
  • diseases of the ear, nose, throat, respiratory tract and lungs ( , pleurisy );
  • generalized septic lesions;
  • other diseases associated with streptococcus ;
  • prevention of nosocomial infections associated with streptococcus .

Contraindications

Sensitization to the drug.

Side effects

Not found.

Instructions for Streptococcal Bacteriophage (Method and dosage)

The instruction allows the use of the drug inside, in the form of irrigation, applications, enemas, introduction into the nasal cavity, wounds, uterus, vagina, sinuses, as well as for drainage of the cavities. Recommended dosages for patients over 8 years old are up to 30 ml of solution (oral administration) and up to 50 ml (administration in the form of enemas). Treatment of localized diseases of a purulent-inflammatory nature should be carried out by a combination of local treatment and oral administration of the drug for 1-3 weeks.

Depending on the nature of the infection, the agent can be used in the following ways:

  • In the form of lotions, plugging and irrigation in an amount of up to 200 ml. At abscess after emptying its cavity, the drug is administered orally in a smaller amount than the amount of removed pus. When treating osteomyelitis 10-20 ml of the agent is injected into the wound after surgical treatment.
  • When injected into the pleural, articular or other limited cavities, capillary drainage is installed, through which the drug is injected in 100 ml for several days.
  • At pyelonephritis, cystitis, urethritis the agent is taken orally. In the case of draining the cavity of the renal pelvis or bladder, the drug is administered through the stoma twice a day, 30-40 ml into the bladder cavity or 6-7 ml into the renal pelvis.
  • At gynecological lesions of a purulent-inflammatory nature the agent is injected into the uterine cavity or vagina, 7-10 ml every day. At colpitis - Irrigation of 10 ml or tamponing twice a day for 2 hours.
  • At diseases throat, ear and purulent-inflammatory nose the agent is administered at 2-10 ml up to three times a day. The bacteriophage is used for washing, instilling, rinsing, introducing turunda for 1 hour.
  • At intestinal dysbiosis and enteric infections the drug is taken orally three times a day one hour before meals for 1-3 weeks. It is also allowed to combine double oral administration with joint rectal administration of an age-specific dose once a day in the form of an enema after defecation.

Use of the drug in children under 6 months of age, including premature babies

At enterocolitis, sepsis newborns Bacteriophage streptococcal is administered by setting high enemas of 5-10 ml up to three times a day. It is also possible to use by mouth by mixing with breast milk. The course of treatment lasts up to 15 days.

In order to prevent enterocolitis, sepsis in case of intrauterine infection or the risk of nosocomial infection in newborns, the drug is used twice a day in the form of enemas for a week.

When treating pyoderma, omphalitis, septic wounds the agent is used in the form of applications with a soaked gauze cloth twice a day.

Overdose

Such cases have not been described.

Interaction

The drug is allowed to be combined with anti-inflammatory and antibacterial agents.

If before using the Bacteriophage for processing were used antiseptics , then the wound must be washed with a solution sodium chloride .

Terms of sale

Over the counter.

Storage conditions

Keep out of the reach of children. Store in a dark place at a temperature of 2-8 degrees.

Shelf life

special instructions

Before use, the vial with the drug must be shaken and its transparency and the presence of sediment must be assessed. If turbidity or sediment is detected, the drug must not be used!

Due to the presence of a favorable climate in the preparation for the development of microorganisms from the environment, which cause turbidity of the solution, the opening of the bottle should be carried out according to the following rules:

  • hands must be washed thoroughly;
  • before removing the cap, it must be treated with an alcohol solution;
  • the cap should be removed without removing the stopper;
  • if, during opening, the cork was accidentally uncorked together with the cap, then it should not be placed on the table with its inner surface, and the bottle should not be left open (after taking the product, it must be closed with a cork);
  • the opened bottle must be stored in the refrigerator.

If these rules are observed and there is no turbidity, the agent from the opened bottle is allowed to be used throughout the entire shelf life.

For children

Standard doses of the drug for children under 6 months are 5 ml when taken orally and 10 ml when used as an enema; for children 6-12 months old - 10 ml when taken orally and 20 ml when used as an enema; for children 1-3 years old - 15 ml when taken orally and 20-30 ml when used as an enema; for children 3-8 years old - 20 ml when taken orally and 30-40 ml when used as an enema. In children over eight years old, adult doses of the drug are used.

Newborn

The standard dose for newborns is 5 ml when taken orally and 10 ml when used as an enema.

During pregnancy and lactation

It is allowed to use the medicine during the indicated periods under the supervision of a doctor.

The drug "Streptococcal bacteriophage" is

This medicine is produced in the form of solutions for oral, external and local use. It is a clear yellowish liquid (20 ml in a transparent bottle, in a cardboard box of 10 or 4 bottles of 100 ml). The active component is sterile filtrate of phagolysates of streptococcal strains, the auxiliary component is 8-hydroxyquinoline sulfate monohydrate. In the form of tablets, "Streptococcal bacteriophage" is not released.

Pharmacological properties

The pharmaceutical product specifically lyses the bacteria of this species.

According to the instructions for use, "Streptococcal bacteriophage" is a specific type of viruses that affect the cells of streptococcus bacteria, provoking their selective destruction. So the drug quickly eliminates the manifestations of the infectious process. Moreover, this bacteriophage specifically affects only the cells of Streptococcus representatives, without destroying other cells of the body, without affecting the quantitative and qualitative composition of the microflora. Thus, this medication can be considered safe for humans.

Indications for appointment

As indicated by the instructions for use, "Streptococcal bacteriophage" is recommended for the prevention and treatment of diseases, the development of which is provoked by Streptococcus bacteria, as part of a complex treatment. Such pathologies include:

  • urogenital diseases: pyelonephritis, urethritis, cystitis, salpingo-oophoritis, colpitis, endometritis;
  • surgical infections: carbuncles, hydradenitis, boils, felon, mastitis, abscess, purulent wounds, phlegmon, burns, paraproctitis, osteomyelitis, bursitis;
  • pathology of ENT organs, lungs and respiratory tract: otitis media, sinusitis, tonsillitis, laryngitis, tracheitis, pharyngitis, bronchitis, pneumonia, pleurisy;
  • generalized septic diseases; purulent and inflammatory pathologies in newborns and infants: conjunctivitis, omphalitis, pyoderma, sepsis, gastroenterocolitis, etc.;
  • enteric infections, intestinal dysbiosis; cholecystitis, gastroenterocolitis;
  • other diseases caused by infection with streptococci.

For prevention

For prophylactic purposes, "Streptococcal bacteriophage" is used for external treatment of infected wounds and stitches after surgery, as well as to prevent development. One of the main conditions for effective therapy with this immunobiological medication is the preliminary establishment of the phagocytic sensitivity of the causative agent of the disease.

Many people wonder how to take "Streptococcal bacteriophage"? The use of this medication is contraindicated in case of high sensitivity to its components.

Method of administration and dosage

Means "Bacteriophage streptococcal" is used rectally, orally, in the form of applications, irrigation, by introduction into the nasal cavity, in the wound cavity, vagina, paranasal sinuses, uterus and drained cavities.

  • 0-6 months - 6-10 ml;
  • 6-12 months - 10-20 ml;
  • 1-3 years - 20-30 ml;
  • 3-8 years old - 30-40 ml;
  • 8 years and more - 40-50 ml.

When treating with "Bacteriophage streptococcal" purulent and infectious phenomena with localized lesions, this medication should be used simultaneously locally and orally for 7-21 days (depending on clinical indications).

If certain chemical antiseptics have been used before using the medicine to treat wounds, the wound should be thoroughly rinsed with sterile sodium chloride solution.

The method of use and dosage of the drug "Streptococcal bacteriophage", depending on the localization of the infectious focus (pleural, articular or other limited cavities) is as follows: up to 100 ml is injected and a capillary drainage is installed, with the help of which the medication is injected over several days. For purulent wounds, this remedy is used in the form of applications, dressings, irrigations in a volume of up to 250 ml, taking into account the area of ​​the inflamed area. With an abscess, after opening the cavity and removing its contents using a puncture, the drug is injected in a smaller volume than the volume of the removed pus. With the development of osteomyelitis, 10-20 ml is poured into the wound cavity after surgical treatment by means of drainage or turunda.

When cystitis, pyelonephritis, urethritis liquid "Bacteriophage streptococcal" is taken orally. In cases where the cavity of the bladder or renal pelvis has been drained, the drug is poured 2 times a day through a cystostomy or nephrostomy.

In case of inflammation of the ENT organs, it is administered 3 times a day at a dosage of up to 10 ml into the nasal cavity or middle ear. The medication can be used in the form of instillation, rinsing, rinsing and the introduction of turunda, which are left in the inflamed cavity for 1 hour.

With colpitis, irrigation with this agent in a volume of 10 ml or tamponing is carried out 2 times a day. In case of purulent-inflammatory pathologies of the female genital area, 5-10 ml is injected daily 1 time a day into the vagina or uterus.

With intestinal dysbiosis and enteral infections, the medication is taken orally one hour before meals, 3 times a day, 7-21 days according to clinical indications. It is allowed to combine oral administration of a medicine with rectal administration of a single age dose in the form of an enema after mandatory bowel movement.

For kids

The recommended dosages of "Streptococcal bacteriophage" for children - at the age of less than six months with sepsis and enterocolitis, this medicine is administered 3 times a day, 10 ml each in the form of high enemas (through catheters or gas tubes). If the child does not regurgitate, the bacteriophage is prescribed orally, while it must be mixed with breast milk, parallel rectal administration and ingestion of this medication for a course of 5-14 days is also possible.

Undesirable side reactions during therapy with this drug have not been established.

Before using this medication, shake the bottle and check for sediment or cloudiness. It is allowed to use only a clear solution that does not contain sediment. Due to the fact that the drug "Streptococcal bacteriophage" has a nutrient medium in which bacteria from the external environment can multiply, it becomes cloudy and a sediment is formed.

It is necessary to open the bottle in compliance with the following rules:

  • wash your hands thoroughly;
  • wipe the cap and hands with an alcohol solution;
  • remove the cap;
  • do not touch the inside of the cork to the table or other objects;
  • always leave the bottle closed;
  • the opened bottle should be kept in the refrigerator.

You can extract the required volume of a medical product using a sterile syringe by piercing the stopper.

There are no data on the possible effect of this pharmacological agent on the ability to drive cars and other mechanisms.

Use in pregnancy and breastfeeding

During pregnancy and lactation, "Streptococcal bacteriophage" is used to treat infectious diseases caused by bacteria that are sensitive to it. The drug should be used under medical supervision.

Price

This medication has an approximate cost of 800-900 rubles. It depends on the region and the pharmacy chain.

Analogues of "Streptococcal bacteriophage"


Content

With increased activity of streptococcus, doctors prescribe the drug streptococcal bacteriophage, which can be bought over the counter without a prescription. Real patient reviews and a detailed study of the instructions should not become a guide to use, additional specialist advice is required.

What is streptococcal bacteriophage

If the pathogenic flora is not exterminated in a timely manner, the disease intensifies its symptoms and is fraught with serious health complications. Streptococcal bacteriophage is a specific medication that belongs to the pharmacological group of immunobiological drugs. The active ingredient is live bacteriophages, which, when interacting with harmful streptococci, efficiently destroy the latter. The bacterial lysate is contained in a special solution, which has an individual dosage, intended for oral and subcutaneous oral administration.

The streptococcal bacteriophage is active against all types of Streptococcus, and the lysate present in the natural composition strengthens the weakened immune system, additionally trains the immune cells. Such conservative treatment is relevant only as prescribed by the attending physician, who additionally determines the appropriate form of release, dose, intensive care course, according to the prevailing disease.

Instructions for use

Self-medication is completely excluded at any age. Detailed instructions for the use of streptococcal bacteriophage informs about indications and contraindications, specifies potential side effects, cases of overdose. The main advantages of prescribing streptococcal bacteriophage are natural composition, mild action in the body, stable therapeutic effect, unlimited age category of patients. The disadvantage of such treatment is the selective effect on the focus of pathology. In this case, doctors will have to find a more effective analogue.

Indications for use

The bacteriophage has a pronounced anti-streptococcal effect, is used for adults and in the intensive care regimen for newborns. Before treating streptococcal infection, it is required to determine the etiology of the pathological process and determine an effective treatment. The main medical indications for the use of streptococcal bacteriophage, reflected in the detailed instructions, are as follows:

  1. Purulent-inflammatory processes of ENT practice and respiratory tract: sinusitis, otitis media (otitis media), streptococcal rhinitis, tonsillitis, sinus inflammation, laryngitis, pharyngitis.
  2. Urogenital infections: chronic pyelonephritis, inflammation of the uterine appendages in women, surgical infections after surgery, urethritis, colpitis, cystitis, salpingo-oophoritis, endometritis, progressive prostatitis in men.
  3. Lower respiratory tract infection: bronchitis, tracheitis, pleurisy, pneumonia, pneumonia. Such an appointment is appropriate for angina and other diseases of the throat, prone to suppuration, the formation of abscesses.
  4. Inflammatory processes of the skin of an infectious nature: pyoderma, carbuncles, wound suppuration, burns, phlegmon, hydradenitis, boils, abscesses, any infections of streptococcal origin.
  5. Infection of the digestive tract: intestinal dysbiosis, gastroenterocolitis, enteral infections, empyema of the gallbladder, pancreatitis, cholecystitis, paraproctitis, any disorders of the digestive system.
  6. Purulent-inflammatory diseases in newborns: enterocolitis, sepsis, pyoderma, omphalitis, conjunctivitis.
  7. Streptococcal abscess: Any soft tissue lesion followed by infection and suppuration.
  8. Generalized septic diseases.
  9. The rehabilitation period after surgical treatment, prevention with streptococcal bacteriophage: mastitis, paraproctitis, abscess, bursitis, panaritium, osteomyelitis.

Contraindications

This liquid medicine for streptococci is in tangible demand in modern medicine, it is equally prescribed for adults and children. However, such conservative treatment and prevention is not allowed for all patients. The instructions reflect the medical contraindications of streptococcal bacteriophage, which limit the list of possibilities of a typical medication. It:

  • increased activity of the body towards the natural components of the bacteriophage;
  • chronic tendency to allergic reactions;
  • increased activity of other bacteria, strains insensitive to live bacteriophages.

Dosage

The medicinal solution is intended for oral and external use, and the method of using the drug and its daily dosage depends on the nature of the pathological process, the age of the clinical patient. All appointments are made only by the attending physician. The dosage of streptococcal bacteriophage recommended in the detailed instructions is presented below, it can be adjusted purely individually. It:

  1. Irrigation of the skin and mucous membranes in the inflammatory process of an infectious origin.
  2. Catheterization with exacerbation of infections of the genital organs and bladder, intramuscular infections - with inflammation of the subcutaneous tissue.
  3. Mouthwash for productive treatment of throat diseases, dental infections. Additionally, the use of an aerosol solution is allowed.
  4. Oral administration of streptococcal bacteriophage for the treatment of gastrointestinal tract pathologies: daily dose for adults - 25-40 ml, for children - 5-15 ml.
  5. Tamponing - introduction into the outer ear cavity, nasal passages, depending on the predominant focus of pathology.
  6. Inhalation of an aerosol of a solution for the etiological therapy of inflammation of the upper and lower respiratory tract.
  7. Rectal administration of streptococcal bacteriophage for the treatment of the lower gastrointestinal tract at daily doses of 10-50 ml.
  8. Lotions and washing of the dermis in case of soft tissue damage followed by infection and suppuration.
  9. Introduction into the articular or pleural cavities up to 100 ml, then leave a capillary drainage for the intake of staphylococcal bacteriophage for several days.
  10. The medicine can be injected in a volume of 2-10 ml up to three times a day for purulent-inflammatory diseases of the ENT practice.

Side effects

Before starting treatment with streptococcal bacteriophage, it is required to examine the blood serum for the detection of a pathogenic infection. Only on the recommendation of a doctor, you can order and buy this medicine in the online store, use it strictly for medical reasons. In practice, there are no side effects of streptococcal bacteriophage, however, in isolated cases, local, allergic reactions may occur on the skin.

Analogs of streptococcal bacteriophage

If the specified drug is not on sale, or its effect in practice turned out to be weak, mediocre, it is necessary, together with the attending physician, to introduce an equally worthy replacement. The most common analogs of streptococcal bacteriophage can also be found in the catalogs of online pharmacies, their cost is different, but the approval of a specialist is required. Alternatively, it can be the following medicines:

  • Pyobacteriophage;
  • Bacteriophage Klebsiella pneumonia;
  • The bacteriophage is polyvalent;
  • Streptophage;
  • Protein bacteriophage, staphylococcal and coliprotein.

The price of a streptococcal bacteriophage

For some, the indicated medication is inexpensive, while others consider its cost in the pharmacy unnecessarily overpriced, inaccessible. The price in the online pharmacy is lower than the retail pharmacy rates, so the virtual purchase is more profitable for the patient. Before buying a medicine, it is better to consult a doctor, to determine the pharmacy with the lowest price for streptococcal bacteriophage. Below are the places where you can buy the indicated medicine.

Streptococcal bacteriophage (Bacteriophagum streptococci)

Composition

Streptococcal bacteriophage solution contains:
Sterile filtrate of Streptococcus bacteria phagolysates.
Additional ingredients including water and preservative.

pharmachologic effect

Streptococcal bacteriophage is a drug with a specific antimicrobial effect against streptococci. The bacteriophage causes lysis of sensitive strains of streptococci, due to the penetration of phage particles into the bacterial cell and the use of its resources for reproduction. After the death of the bacterium, the release of mature phage particles is noted, capable of infecting other sensitive bacterial cells.
The streptococcal bacteriophage does not affect the vital activity of other bacteria, in particular, it does not change the natural microflora.
The effectiveness of the drug increases in the case of preliminary determination of the phage sensitivity of the pathogen.

Indications for use

Streptococcal bacteriophage is used to treat diseases caused by streptococci, regardless of the localization of the inflammatory process.
In otolaryngological and pulmonological practice, bacteriophage is used to treat patients with otitis media, sinusitis, sinusitis, angina, laryngitis, pharyngitis, bronchitis, tracheitis, pneumonia and pleurisy.
Streptococcal bacteriophage is used to treat surgical, urogenital and enteric infections, including burns, boils, infected wounds, abscesses, bursitis, osteomyelitis, mastitis, hydradenitis, cystitis, colpitis, endometritis, salpingo-oophoritis, as well as cholecystosis and dysbacteriosis.

Streptococcal bacteriophage is used to treat generalized septic diseases, as well as pyoinflammatory diseases in newborns, including omphalitis, conjunctivitis, pyoderma and sepsis.
It is recommended to prescribe a bacteriophage for the treatment of postoperative and freshly infected wounds to prevent the development of a purulent-inflammatory process.
According to epidemic indications, streptococcal bacteriophage is prescribed for the prevention of nosocomial infections.

Mode of application

Streptococcal bacteriophage is intended for oral, local and rectal administration. The drug is taken orally undiluted 60 minutes before meals. The duration of therapy, the regimen of application and the dose of the bacteriophage are determined by the doctor.
When treating diseases with localized pyoinflammatory lesions, it is necessary to use the drug both locally and orally.

Depending on the localization of the focus of infection, the bacteriophage is used:
- For topical application, including irrigation, applications, lotions, tamponing and wetting of turundas introduced into the cavity. In this case, up to 200 ml of solution is used, depending on the size of the affected area. In case of abscesses, a bacteriophage is injected into the cavity after the removal of pus (the amount of the drug should be slightly less than the volume of the removed pus). In osteomyelitis 10-20 ml of the drug Streptococcal Bacteriophage is poured into the wound after surgical cleaning.
- For introduction into the articular, pleural and other limited cavities, including the cavity of the bladder and renal pelvis, through capillary drainage, nephrostomy or cystostomy. Up to 100 ml are injected into limited cavities, up to 50 ml into the bladder, up to 7 ml into the renal pelvis.
- In gynecological practice, 5-10 ml of the solution is injected into the uterine cavity or vagina. It is allowed to use a solution for wetting tampons inserted into the vagina.
- In otolaryngological practice, the solution is used for wetting turundas, rinsing, rinsing and instilling.
- For intestinal infections, the drug is used for oral and rectal administration. The drug is administered rectally in the recommended single dose in the form of a high enema.
As a rule, a single dose recommended for the corresponding age group of the patient is prescribed orally three times a day. For combined rectal and oral administration, one oral dose is replaced by rectal administration.

Recommended single doses of Bacteriophage streptococcal for different age groups:
Children under 6 months of age are generally advised to administer 5 ml of the solution orally or 10 ml for rectal administration. Therapy should be started with rectal administration of the solution in the form of high enemas, if within 2-3 days of treatment there is no development of regurgitation and vomiting, it is allowed to prescribe oral administration of a bacteriophage.
For children 6-12 months old, it is generally recommended to administer 10 ml of solution orally or 20 ml for rectal administration.
For children 1-3 years old, as a rule, it is recommended to prescribe 15 ml of solution orally or 30 ml for rectal administration.
Children 3-8 years old, as a rule, are recommended to prescribe 20 ml of solution orally or 40 ml for rectal administration.
Children from 8 years old and adults, as a rule, are recommended to prescribe 30 ml of solution orally or 50 ml for rectal administration.

The average duration of therapy is 7 to 20 days. With recurrent forms of the disease, several courses of bacteriophage treatment are prescribed.
Therapy with Streptococcal Bacteriophage does not exclude the prescription of antibiotics.
When applied topically, if the wound is treated with chemical antiseptics, before using the bacteriophage, the affected area should be washed with isotonic sodium chloride solution.

Side effects

There was no development of undesirable effects of the drug Bacteriophage streptococcal.

Contraindications

It is not advisable to prescribe the drug to patients with intolerance to additional or active components of the bacteriophage.

Pregnancy

During pregnancy, the question of the advisability of using the drug Bacteriophage streptococcal is decided by the doctor.

Drug interactions

Streptococcal bacteriophage can be used simultaneously with other drugs, including antibiotics of various groups.

Overdose

There are no data on an overdose of the drug Bacteriophage streptococcal.

Release form

Solution Bacteriophage streptococcal 20 or 100 ml in glass vials, 1 vial is placed in a carton pack.
Solution for injection Streptococcal bacteriophage, 10 ml in ampoules, 10 ampoules are placed in a cardboard box.

Storage conditions

The streptococcal bacteriophage is valid for 2 years if stored in rooms with a temperature regime of 2 to 8 degrees Celsius.
It is forbidden to freeze the streptococcal bacteriophage solution.
It is allowed to transport the drug Bacteriophage streptococcal at temperatures up to 25 degrees Celsius for no more than 1 month.

Nosological classification (ICD-10)

Other bacterial intestinal infections (A04)

Diarrhea and gastroenteritis of suspected infectious origin (A09)

Streptococcal septicemia (A40)

Streptococcal infection, unspecified (A49.1)

Streptococci and staphylococci as the cause of diseases classified elsewhere (B95)



 
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