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Mydocalm from the waist. Pills for back pain mydocalm. General indications for the use of funds

Muscle relaxants in osteochondrosis are used for spasms of deep muscles due to pinching of the nerve processes by deformed intervertebral discs. Muscle relaxants are drugs of narrowly targeted action, and not a panacea for treatment - a tool that contributes to the effective use of complex treatment of osteochondrosis.

Introduction

The need to prescribe muscle relaxants is caused by limited mobility or complete immobility of the vertebrae, in which there is severe pain at the slightest movement, caused by compensatory spasm of certain muscles. The desire to eliminate or relieve pain in osteochondrosis should not lead to the thoughtless use of advertised drugs, especially on the advice of friends. Only a doctor will make an accurate diagnosis, prescribe the appropriate muscle relaxants for osteochondrosis and the correct dose of medication.

Indications for use

Indications for taking muscle relaxants are:

1. Aching and pressing pains localized in certain places of the back (upper edge of the trapezius muscle, paravertebral muscles, deep muscles of the lumbar region).
2. "Pulsatilla" or lumbago, the manifestation of which is a sudden sharp shooting pain with sudden movement, coughing, sneezing due to a pinched nerve.
3. Inflammation or pinching of the nerve with subsequent pain syndromes up to numbness and loss of tactile sensitivity of the extremities (the most common cases are pinching of the sciatic nerve).

Impact principle

Muscle relaxants are divided into:

• Peripheral drugs (application - traumatology);
• Drugs of central action (application - neurology).

The body reacts to pain in osteochondrosis with a strong muscle spasm, which fixes the affected spine in a certain position, immobilizing it and protecting it from damage. The corresponding protective reaction becomes pathological, supporting the pain syndrome, when the muscle spasm continues for a long time. Lactic acid accumulates in the muscles, causing pain, which causes a new spasm.

To remove muscle tone is necessary for the effectiveness of the course of treatment. This is facilitated by muscle relaxants of the central effect, which:

1. Reduce or completely eliminate muscle spasm.
2. They make it possible to reduce the dose of anti-inflammatory drugs, which leads to the prevention of various side effects from drugs.
3. Increase the effectiveness of complex treatment.

List of drugs

The names of muscle relaxants are listed according to the main active ingredient.

Tizanidine:

• Sirldalud;
• Tizanil;
• Thezalud;
• Tizanidin-teva.

Tolperisone:

1. Tolperil.
2. Tolperisone-OBL.

Gamma aminobutyric acid: baclofen.

The following muscle relaxants are most often prescribed from this list:

Reduces muscle tone by inhibiting the polysynaptic transmission of excitation by spinal cord neurons. It has an analgesic effect.

It is used for acute muscle spasms, restores mobility. Absorbed almost completely within a short time. Metabolized in the liver, excreted by the kidneys.

1. Patients with severe liver dysfunction.
2. Patients under 18 years of age.
3. With sensitivity to the composition of the drug.

Available in the form of tablets in doses of 50 mg and 150 mg, as well as in the form of 1 ml ampoules.

Take one or two tablets three times a day. In some cases, an additional tablet may be taken at bedtime. The dose is prescribed by the doctor.

The course of administration begins with a daily dose of 6 mg with a gradual increase to 12-24 mg per day.

Do not take simultaneously with Fluvoxamine, Ciprocloxamine.

Side effects:

• bradycardia;
• Reduces blood pressure;
• Vomit;
• dry mouth;
• bowel disorder;
• Increases the activity of liver enzymes (possible hepatitis);
• General muscle weakness;
• General fatigue, drowsiness.

Due to the above side effects, it is necessary to stop driving while taking a muscle relaxant and take into account that the drug reduces concentration. Once a month, check liver enzymes for the degree of activity.

It blocks spinal mono- and polysynaptic reflexes, inhibits the conduction of impulses in primary afferent fibers and motor neurons. It has a membrane-stabilizing, local anesthetic, adrenoblocking, weak antispasmodic effect. With osteochondrosis, it enhances peripheral blood flow, completely independent of the influence of the central nervous system.

It is taken 2-3 times a day after meals, 50 mg. During the course of admission, the dose gradually increases to 150 mg per dose (daily dose of 450 mg).

1. Children under 1 year old.
2. With myasthenia.
3. With special sensitivity to the composition of the drug.

Side effects:

• Headache;
• Reduces blood pressure;
• Nausea, vomiting;
• abdominal discomfort, muscle weakness;
• In rare cases, allergies.

It is not prohibited to take it simultaneously with sedatives, hypnotics and dosage forms containing alcohol.

Allowed to drive a car.

It has an antispastic effect, which contributes to the inhibition of spinal and visceral reflexes, reducing muscle tension. It has an analgesic effect.

Available in the form of tablets in doses of 10 mg and 25 mg.

It is taken three times a day, 2 tablets. With an interval of 3-5 days, the dose should be gradually increased to 100 mg per day.

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1. Epilepsy, convulsions.
2. Parkinson's disease.
3. Chronic renal failure.
4. Atherosclerosis.
5. Cerebrovascular insufficiency.
6. Peptic ulcer of the stomach and duodenum.
7. Pregnancy and breastfeeding.
8. Children up to 12 years old.

Side effects:

• Rapid fatigue, dizziness, drowsiness;
• Depressive state;
• dry mouth;
• Tremor and convulsions;
• Retention of urine and stool;
• With prolonged use, a decrease in kidney function.

Precautionary measures

Those taking a muscle relaxant, in the presence of liver disease and diabetes, it is necessary to monitor the level of sugar in the blood, and once a month, liver enzymes should be checked for the degree of activity.

Any muscle relaxants for osteochondrosis are not used without medical supervision. The dose of the appropriate muscle relaxant is prescribed by the doctor based on the patient's history. In case of side effects from taking an increased dose, immediate assistance will be provided, drugs will be canceled and an alternative treatment for osteochondrosis will be prescribed.

• Indications
• Application scheme
• Solution in ampoules
• The effect of the drug on pregnancy
• Efficiency
• Overdose
• Analogues

Mydocalm is a modern pharmacological agent used to eliminate pain. The drug has an effect on the central nervous system, so it is not recommended to take it without medical supervision. And this is especially true for medicine in ampoules. In some cases, they can cause suffocation, lack of air.

Indications

As a rule, the doctor prescribes Mydocalm if there are indications for use, such as:

• ischemic stroke, vasospasm in the brain;
• encephalopathy;
• multiple sclerosis;
• myasthenia gravis of central nervous origin;
• pain syndrome caused by sciatica, osteochondrosis, including lumbago;
• rheumatoid arthritis, deforming osteoarthritis;
• thrombophlebitis of the lower extremities;
• obliterating endarteritis;
• pronounced severe pain syndrome against the background of the development of hemorrhoids;
• menstrual pain;
• the threat of miscarriage due to hypertonicity of the muscular structures of the uterus;
• renal colic;
• cholelithiasis.

The drug mydocalm in tablets and injections according to the instructions for use is prescribed during the rehabilitation period after various surgical interventions. It has a positive effect on the level of stretching of muscle fibers.

The scheme of application of the drug

The scheme of use by the doctor is drawn up based on the severity of the symptoms and the patient's tolerance for the drug Mydocalm.

Usually the daily dose of the drug in tablet form for adult patients is 150-450 mg, divided into three doses. Reception begins with a minimum dosage of 50 mg three times a day. If there is no effect, the dose is increased.

When prescribing the drug in the form of intramuscular injections, it is prescribed 200 mg per day (in 2 doses), with intravenous administration, the daily dose is 100 mg (in 1 dose).

With intravenous administration of mydocalm, the doctor uses the drip method, which is considered the most effective. Intramuscular injections also act quickly. The price of the medicine in ampoules is around 300 rubles, but it justifies the money spent.

Small patients, aged 3 months. - 7 years Mydocalm is prescribed based on weight: 5-15 mg / kg (three times a day). Older patients - 7-15 years old - are recommended orally 3-5 mg / kg per day (three times a day). The drug is taken with food.

Side effects and contraindications

If there is a reaction to the components that make up the drug, this manifests itself in the form of side effects:

• headache;
• nausea, vomiting;
• muscle weakness.

Allergic manifestations are possible: itching; erythematous rashes; angioedema.

With improper jet administration intravenously (this is highly undesirable), arterial hypotension often occurs. If you reduce the dosage, as a rule, signs of side effects disappear or become less pronounced.

Contraindications. In medicine, it has been established that Mydocalm cannot be used if there are contraindications:

• myasthenia gravis;
• if the patient is allergic to the drug lidocaine (when prescribing an ampouled form) or tolperisone;
• children under the age of 3 months.

Solution in ampoules

Mydocalm Richter is a solution intended for the administration of the drug intramuscularly, intravenously. The solution is almost colorless, has a slightly greenish tint and a specific smell. According to the instructions for use, the composition of the drug includes tolperisone hydrochloride and lidocaine hydrochloride. This provides a local anesthetic effect.

Prescribing the drug during pregnancy

To date, there is no evidence that mydocalm is absolutely harmless to pregnant and lactating women. However, it is prescribed in medical practice for pregnant women (in the first trimester), as well as for lactating women, if necessary. At the same time, it is important that the positive therapeutic effect that the patient wants to receive does not cause the risk of negative consequences for the fetus or newborn.

Efficiency

Mydocalm has been successfully used in many countries. It is well tolerated, and does not have a sedative effect on the body, which was proven in a randomized trial, which used a placebo. In addition, patients who took this drug, reviews of Mydocalm Richter in injections and tablets left only positive. Only in isolated cases, therapy was ineffective.

Overdose

Overdose cases are extremely rare, since the therapeutic threshold is quite high, and even a dose of 600 mg, as a rule, does not cause signs of an overdose. In the event of shortness of breath, convulsions, suffocation, lack of air, gastric lavage is recommended. There is no antidote therapy.

Price

The price of Mydocalm in tablets of 50 mg is 191 rubles, 150 mg - 222 rubles per package with 30 dragees. It is very important to clarify with the doctor the required dosage and concentration of the substance. The drug is potent, and therefore it is released from pharmacies only by prescription. The medicine should be stored in a dark place, out of the reach of children, at a temperature of 8°-15°C.

Analogues

Sometimes a doctor may prescribe an analogue of Mydocalm, for example, Tolperisone, Tolperil, Tolperisone hydrochloride. Their cost is not much different from the price of Mydocalm. You should be aware that treatment with Mydocalm does not affect the psychological state of patients in any way, does not affect attentiveness when driving a car and performing any work associated with increased danger.

According to the instructions, Mydocalm does not reduce its effect when drinking alcohol.

In combination with niflumic acid, the drug enhances its effect, allowing you to achieve a stronger anti-inflammatory and analgesic effect. When a doctor prescribes this medication additionally, the price of treatment does not increase much, since the cost of niflumic acid is not high.

The treatment of back pain with Mydocalm is quite successful, patients feel immediate relief. In some cases, the doctor may prescribe a second course of taking the drug.

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To date, pharmacological companies have learned how to create hormonal drugs that are used to treat chronic and acute diseases, one of these drugs is Dexamethasone injections. Preparations of this type are synthesized analogues of those hormones that are produced by the body.

For the treatment of diseases that are inflammatory in nature, drugs are used that are analogues of glucocorticoids, which are produced by the adrenal cortex. With their help, you can get rid of the inflammatory process, an allergic reaction or diseases of the joints.

The drug Dexamethasone is included in this group. Now the medicine is common in the treatment of joints, for this reason it is necessary to know about all aspects of its use.

Operating principle

Dexamethasone is made by changing the structure of a glucocorticoid called hydrocortisone. The tool is widely used in various areas of medicine due to the fact that it has many effects. The course of treatment and dose are determined by the doctor.

The principle of action of the drug is associated with the following effects

• when the drug enters the body, this leads to the reaction of the receptor protein, which is located on the cell membranes and enters the cell nucleus on the first day;
• for several days, the phospholipase enzyme is inhibited due to the launch of many metabolic processes;
• arachidonic acid does not ferment, and it forms many inflammatory mediators;
• the process of protein breakdown slows down due to the suspension of proteolytic enzymes;
• the state of cell membranes is stabilized, the vessels are strengthened, due to which inflammatory cells do not come out of them;
• there is a blocking of the protein compliment system, which is part of the inflammatory process;
• the immune system produces fewer white blood cells.

Due to the above effects, Dexamethasone has an effect

• antishock;
• antiallergic;
• immunosuppressive;
• anti-inflammatory.

Negative influence

Although this drug is used many times in the event of a disease associated with the joints, it is hormonal, which can lead to a negative effect on the body. The fact is that the effectiveness of the drug lies in the action of glucocorticoids not only on inflammation, but also on metabolism. In this case, it is worth considering contraindications, and the dose should not exceed that prescribed by the doctor. You need to inject Dexamethasone for a strictly prescribed number of days.

Dexamethasone is a hormonal drug that

• Reduces immunity, there is a risk of tumors and infections.
• It inhibits the absorption of calcium, which leads to poor bone formation. This can provoke osteoporosis, it all depends on how much tissue production is stopped.
• Promotes the redistribution of adipose tissue in the body. The limbs become thin, and fat is deposited in the trunk.
• Reduces the production of adrenocorticotropic hormone, and also retains sodium ions and water in the kidneys.

To avoid the above effects when using Dexamethasone in ampoules when injected intramuscularly or directly into the joint cavity, the dose should be minimal, and the number of days of treatment should not exceed those indicated by the doctor.

path in the body

Dexamethasone comes in several forms. It's being used

• locally - in the joint cavity, on the conjunctiva of the eye, skin;
• parenterally - when injections are administered intramuscularly and intravenously;
• inside - taking pills.

Regardless of the form of administration, the drug goes through the same route of excretion and metabolism.

Intramuscular injection helps the substance to quickly enter the bloodstream. Intravenous administration promotes instant hit.

Through the blood, the medicine penetrates into the inflamed area - the site of an allergy or a joint. This drug is able to penetrate into any part of the body, even through the blood-brain barrier or the placenta.

Further path of the drug

1. When the effect is rendered, the substance penetrates back into the bloodstream.
2. Through the blood enters the liver, which makes it inactive.
3. Its metabolites begin to form in the liver 3.5 hours after the onset of influence. The release of tissues occurs after a couple of days.
4. Then the drug enters the kidneys and intestines, through which it is completely excreted from the body.

Regardless of the dosage, the substance, “traveling” through the body, easily enters the milk of a nursing mother.

Indications for use

This drug is indicated for many diseases, but most often for the treatment of allergic reactions and joints, for this reason the latter must be considered in more detail and separately.

Other indications

• when an inflammatory process occurs in the intestine, which has an autoimmune genesis;
• sarkidosis, pulmonary fibrosis, alveolitis;
• inflammatory diseases of the kidneys, in particular glomerulonephritis, which concerns autoimmune mechanisms;
• inflammatory processes on the skin - eczema, dermatitis, psoriasis;
• thyrotoxic crisis, when there is an excessive release of hormones by the thyroid gland, which can lead to death;
• autoimmune diseases of a systemic nature, which are accompanied by an inflammatory syndrome;
• intractable bronchospasm that occurs against the background of asthma;
• cerebral edema, hydrocephalus in oncology, infectious diseases of the brain, hemorrhage, surgery, trauma;
• Dexamethasone is used for back pain caused by inflammation;
• shock of any kind.

Under such conditions, Dexamethasone is taken systemically. The dose and number of days of admission are determined by the attending physician.

Dexamethasone for the treatment of joints

The use of hormonal drugs for the treatment of joint diseases is forced. Such medications are prescribed after non-steroidal drugs have failed.

Dexamethasone in diseases of the musculoskeletal system is used to treat

• Still's disease in adults and children;
• inflammation of the bag of the joint - bursitis;
• in case of soft tissue damage - tendon sprain, tendinitis, periarthritis;
• if the joints are affected by polyarthritis;
• scleroderma or lupus;
• when deforming osteoarthritis is accompanied by synovitis;
• Reiter's syndrome - an inflammatory process in the genitals, eyes and joints;
• ankylosing spondylitis;
• psoriasis, articular syndrome;
• rheumatoid arthritis - removal of the inflammatory process and treatment of other affected organs.

Treatment with Dexamethasone should be prescribed by a doctor and continued for as long as necessary until the inflammation subsides. The drug is administered intramuscularly, intravenously, directly into the joint.

Dexamethasone in the treatment of allergies

When an allergy occurs, treatment with antihistamines is indicated. But in some cases, the reaction is very strong and such remedies cannot have an effect.

The patient is prescribed hormonal anti-inflammatory drugs. They affect mast cells, which leads to the stop of the allergy and the disappearance of all its symptoms.

For allergies, Dexamethasone is used when it occurs

• anaphylactic shock;
• angioedema;
• hives;
• allergies to animals and plants, foods and medicines;
• hay fever, rhinitis - when inflammation appears in the nasal mucosa;
• inflammatory processes on the skin - dermatitis, eczema;
• if angioedema occurs on the neck and face.

But not always these processes need to be stopped using steroid therapy. In this case, the doctor should select the drug.

Contraindications for use

If help is required for shock and Quincke's edema, the contraindication to which attention is drawn is only intolerance to the drug by the body.

Also, when a person needs to use systemic treatment with Dexamethasone, he should pay attention to all contraindications.

According to the instructions for use, there are the following contraindications

1. Intra-articular administration is prohibited in case of infectious processes, a fracture in the joint area, if bleeding is present.
2. Neuralgia, mental illness.
3. Diabetes.
4. Myocardial infarction.
5. Acute period after surgery on the intestines and stomach.
6. Active esophagitis.
7. During exacerbation of ulcers of the duodenum and stomach.
8. Severe form of osteoporosis.
9. active form of tuberculosis.
10. Acquired or congenital immunodeficiency provoked by HIV infections.
11. Fungal, bacterial and viral diseases.

All these factors should be known to the doctor who prescribes the medicine. Otherwise, instead of a positive result, the patient will feel only a worsening condition.

Dexamethasone during pregnancy

Metabolic and active forms of the drug freely enter any organ. For this reason, it is necessary to be careful about hormonal drugs. But sometimes a woman may experience an exacerbation of a chronic disease or acute processes that require immediate help. In this case, it is worth comparing the risks and benefits.

This drug has been assigned class C, which means that the hormone can harm the fetus, but if there is a threat to the health of the woman, its use is considered acceptable.

As for lactating women, it is better for them not to use the drug. If there is a threat to the health of the mother, she should transfer the baby to artificial feeding.

Dexamethasone can harm your baby and fetus in the following ways:

• lead to insufficiency of the adrenal cortex;
• slow down the process of development and growth;
• cause congenital anomalies of the limbs and head;
• create malformations.

Side effects

According to the instructions, the drug can cause the following reactions

• affects the central nervous system and psyche, depression, hallucinations, impaired consciousness may occur;
• after a sharp cessation of the drug, intracranial pressure may increase, this also applies to children;
• violation of electrolyte metabolism, swelling of the hands and feet;
• ulcers can form on the mucous membrane of the digestive tract;
• increased blood clotting, thrombosis;
• drowsiness during the day and sleep disturbance;
• dizziness, headaches;
• violation of the functions of the pancreas and the endocrine system, the work of the adrenal glands is inhibited;
• decrease in bone density, which leads to osteoporosis.

Most often, such consequences are caused by a violation of the dosage, application technique, and the peculiarity of the organism also affects this. Sometimes the patient feels symptoms of any effect even at a low dosage. Therefore, it is important to visit a doctor as often as possible when using Dexametazoc.

Instructions for use

The method and technique of using the drug depends on its form of release. The following are the basic rules for using Dexamethasone by injection:

1. Intravenous use is permissible only when the patient needs urgent help.
2. The intramuscular route of administration involves up to 4 injections per day for adults, and no more than 2 times for children.
3. The introduction into the joint cavity is carried out by a doctor, while the patient must be in a sterile room. The dose is prescribed individually.

Often, for the treatment of joints, together with this drug, Lidocaine is administered, which helps relieve pain.

Table of contents [Show]

About how to take Mydocalm for osteochondrosis, the doctor tells each patient individually. There is no generally accepted standard treatment regimen for this remedy. When prescribing the drug, it is necessary to take into account the individual characteristics of the patient: the severity and duration of the disease, symptoms, age, the possibility of pregnancy in women and body weight for children.

Osteochondrosis is a complex of dystrophic changes in the joints and cartilage. Distinguish cervical, lumbar and thoracic and intervertebral localization pathologists. The latter type is less common than the others, but it becomes the most serious. Therapy of osteochondrosis includes a set of measures that provides for drug correction. Mydocalm has proven itself well among doctors, so experts tend to prescribe this medicine to almost all patients with symptoms of osteochondrosis.

One of the indications for the use of the drug Mydocalm is osteochondrosis. Everywhere, doctors prescribe this medication for patients with its symptoms. At the same time, a person has doubts about the effectiveness of using Mydocalm, because there are different types of diseases, and the drug is always recommended alone. In order to dispel your doubts and understand that with the defeat of any parts of the spine, you can drink medicine, you need to know the principle of its action.

Mydocalm is a drug produced in the form of tablets and solution for injection.

The medicine has the following properties:

• antispasmodic (relaxes muscle tissue during its spasm);
• anesthetic (does not act directly on pain, but eliminates it through relaxation);
• vasodilating (normalizes blood flow);
• sedative (has a calming effect);
• lymphatic drainage (eliminates stagnation in the lymphoid tissue).

With all this, Mydocalm does not affect the functioning of the central nervous system, does not slow down the speed of impulses and does not cause drowsiness. The use of the drug is recommended for all patients with pain in the spine of any localization.

In the treatment of osteochondrosis of the spine with Mydocalm, the effect is achieved due to the effect on the smooth muscles of the skeleton. The drug relaxes the pathologically shrinking tissue, restores its original state. Due to this, blood flow is normalized, pinching of the roots, nerve endings and blood vessels is eliminated.

The dosage of Mydocalm for osteochondrosis is selected individually. If you refer to the instructions, you can find out that the tablets should be drunk three times a day, and the amount of medication for a single dose will vary from 50 to 150 mg. The annotation also describes the method of using injections. Depending on the place of setting, the frequency of administration varies. The manufacturer indicates that in each case the daily dose of the drug and the duration of its use should be established by the doctor, based on the severity of the disease.

Take Mydocalm tablets for osteochondrosis 3 times a day. The initial dose of the drug is 50 mg. With normal tolerability of the drug for a more effective treatment of osteochondrosis, the single volume is gradually increased. If in the first week the patient takes 150 mg per day, then by the end of the second daily norm will be 450 mg.

With osteochondrosis, as well as other indications for use, Mydocalm is taken after meals. The dragee is swallowed whole and washed down with clean water. If the patient does not have the opportunity to swallow the pill whole, then it is permissible to grind it beforehand. The powdered tablet should also be washed down with a sufficient amount of water. A noticeable effect of the drug begins 40 minutes after ingestion.

In severe cases of osteochondrosis, it is recommended to use injections. The same form of the drug is prescribed to patients undergoing treatment in a hospital. With the injection of Mydocalm, the symptoms of osteochondrosis are eliminated faster, which makes it possible to use it in emergency situations, for example, during an attack.

For adult patients, the dosage of the drug usually remains standard. Osteochondrosis of any part of the spine involves intramuscular injection of 1 ml of solution, which is the volume of one ampoule. The frequency of application of injections - twice a day. In a serious condition of the patient or osteochondrosis complicated by cerebral hypoxia, intravenous administration is recommended. A portion of the drug in this case is administered once a day slowly or by means of a dropper. The volume of Mydocalm for intravenous use in osteochondrosis is 1 ml.

Before you start treating osteochondrosis with Mydocalm, you need to make sure that there are no contraindications. Tablets and injections are prohibited if the patient is hypersensitive to the active substance, which is tolperisone. It should be borne in mind that Mydocalm's solution for injection contains lidocaine. Many people, including those suffering from osteochondrosis, are allergic to it.

It is contraindicated to take Mydocalm in Parkinson's disease, epilepsy and psychosis. The doctor must take into account these comorbidities and prescribe alternative drugs for the treatment of osteochondrosis.

The drugs used for anesthesia provoke an increase in the concentration of the active substance Mydocalm in the patient's body. This condition must be taken into account if surgical treatment of osteochondrosis is planned. Psychotropic drugs, which can also be used in the treatment of spinal pathologies, enhance the effectiveness of Mydocalm.

When using drugs based on niflumic acid, the symptoms of osteochondrosis become less noticeable, so drugs with anti-inflammatory and analgesic effects are also used for treatment. The interaction of these drugs with Mydocalm significantly increases their concentration in the body. Therefore, the dose of NSAIDs must be lowered.

The drug Mydocalm does not distort the effect of ethanol on the nervous system and brain, but you should not take the pill with alcohol. If you are planning a feast, then you need to take a dose of muscle relaxant no later than 2 hours before drinking alcohol. The reverse rule also works: after drinking alcohol, you should not immediately take the next dose of Mydocalm. You need to take a break between them for several hours, and before using the pill, be sure to eat.

With osteochondrosis of the cervical region, drinking Mydocalm is recommended in short courses. The average duration of muscle relaxant use is 7 to 14 days. If necessary, this period is extended up to a month. Usually, patients during the treatment period receive a noticeable effect, relieving them of the symptoms of osteochondrosis and constant pain. Further therapy continues with the use of other techniques.

For individuals, the drug Mydocalm is effective, but when it is canceled, the signs of osteochondrosis return. Such patients are forced to take pills for a long time. Numerous experiments and studies have shown that Mydocalm is well tolerated and does not adversely affect the functioning of the body. Therefore, patients with chronic osteochondrosis should not be afraid of long courses of treatment. You can use Mydocalm tablets for 7 years, periodically visiting a doctor and confirming the need for the drug.

In order to carry out effective treatment of osteochondrosis, Mydocalm may require quite a lot. Exactly one package is enough for a course of 10 days. Tablets are available in a volume of 50 and 150 mg of active ingredient. This condition is provided for ease of use. Considering that each pack costs about 400 rubles, for monthly therapy of osteochondrosis, you will have to purchase Mydocalm in the amount of 1200 rubles. Injections are more expensive. Each ampoule of Mydocalm costs about 100 rubles. Often, the treatment of osteochondrosis begins with injections, and after a while they switch to tablets. How to take Mydocalm in this case and after how much to change the method of administering the medicine is determined by the doctor.

The results of treatment of osteochondrosis with Mydocalm in combination with other methods and drugs are usually not long in coming. With proper use and impeccable adherence to the recommendations of a neurologist, relief of well-being comes quickly. Already on the first day of taking Mydocalm, the symptoms of osteochondrosis (in particular, pain) become less noticeable. On the third day of therapy, the maximum effect is achieved. It can be used to evaluate the effectiveness of the use of tablets and the need to increase their dosage.

When Mydocalm is prescribed by a doctor, a person with osteochondrosis should learn in detail about the treatment regimen:

• how to take Mydocalm;
• how many times a day to drink and how many tablets to take at a time;
• whether to use injections instead of pills;
• after what time it is possible to cancel the medicine or reduce its dosage.

Osteochondrosis of the cervical region, which is diagnosed in patients most often, entails dangerous consequences. One of them is cerebral hypoxia. To prevent it, it is necessary to take Mydocalm exactly as much as the doctor prescribed. It happens that patients feel relief from the symptoms of osteochondrosis and stop treatment on their own. At the same time, the spasm of muscle tissue persists, and the vessels continue to supply a small amount of oxygen to the brain. As a result, complications develop, and patients talk about a strange set of circumstances: the treatment was carried out, but did not help.

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Effective shots for back pain

Back pain can only be treated effectively if the cause is known. A variety of diseases and pathological conditions can cause pain in the back: neuralgia, intervertebral hernia, degenerative-dystrophic diseases of the spine, etc.

Before starting to use injections for back pain, it is necessary to undergo an examination, according to the results of which the doctor will prescribe the optimal treatment. Often this requires going through several doctors. In most cases, NSAIDs (non-steroidal anti-inflammatory drugs) and injections of B vitamins are prescribed for the treatment of back pain, muscle relaxants and chondroprotectors can also be prescribed.

In modern medicine, if it is necessary to eliminate back pain, preference is given to drugs from two groups: NSAIDs and neuroblockers. It is important to understand that injections can only be a temporary measure, therefore, after relieving acute pain, it is necessary to use other methods of treatment - therapeutic exercise, massage, physiotherapy, etc.

Doctors often prescribe combined preparations containing B vitamins. It is believed that vitamin B12 has the greatest analgesic effect. Vitamins of this group contribute to the restoration of nerve fibers, normalize nervous and metabolic processes and have an overall positive effect on the nervous system.

However, the use of B vitamins as injections for back pain does not make sense if the pain occurs in an acute condition. If the disease that causes discomfort is chronic or recurs, the use of vitamin-based drugs is ineffective.

In some cases, injections and stretching are used to combat particularly severe pain. The patient lies on his stomach, at the points of the most intense pain, injections are made with a solution of novocaine. In this case, the needle should enter strictly perpendicular. Next, passive stretching of the muscles is performed, after which a hot compress is placed on the affected area. After removing the compress, the patient needs physical activity. It is required to move to the maximum, using the muscles of the diseased area.

This blockade is used to prevent the nerve from transmitting painful impulses. It's like he's turning off. For maximum effectiveness of the blockade, injections should be made as close as possible to the exit points of the nerves. Epidural blocks are most often prescribed for chronic back pain, such as a herniated disc.

The most commonly prescribed B vitamins include:

• milgamma,
• Combilipen,
• neurobion,
• Trigamma.

They have common basic characteristics. The main substances in their composition: Lidocaine, Cyanocobalamin, Pyridoxine, Thiamine. Indications for the use of drugs are such pathologies:

• back pain caused by neurological disorders, including radicular syndrome and intercostal neuralgia, diseases of the spine, the formation of an intervertebral hernia;
• triple nerve neuralgia, neuritis;
• night cramps, polyneuropathy.

These drugs are not prescribed for pregnant women, nursing mothers, patients with heart failure and hypersensitivity to the components of the drug, children.

In some cases, side effects may occur. Rarely, an allergic reaction occurs, tachycardia, increased sweating may occur.

Injections with the use of these drugs are done intramuscularly. As a rule, 2 ml of the drug is prescribed 1 time per day. The course of treatment, depending on the condition of the patient, can be 5-10 days. After that, vitamins may be prescribed in tablet form or 2-3 injections per week for 2 to 3 weeks. Which medicines are best, the doctor will determine.

These drugs are prescribed as part of symptomatic therapy. NSAIDs help relieve pain and reduce inflammation, but they do not fight the causes of pain.

Most drugs in this group are quite toxic and can cause various side effects. Ibuprofen is one of the least toxic drugs. Moreover, all drugs have almost the same anesthetic properties, that is, it is impossible to name more effective and less effective drugs from this group. Therefore, in most cases, it is not worth paying more for NSAIDs.

The most commonly prescribed NSAIDs include:

• Meloxicam (analogues: Movalis, Artrozan, Amelotex);
• Ketoprofen (analogues: Flexen, Ketonal, Flamax, Artrosilene);
• Ketorolac (analogues: Ketorolac, Ketanov, Ketorol);
• Diclofenac (analogues: Ortofen, Naklofen, Vorltaren).

NSAIDs are prescribed for injections for back pain of any etiology.

Contraindications are:

• periods of pregnancy and lactation;
• heart, kidney or liver failure;
• peptic ulcer of the gastrointestinal tract;
• age up to 16 years;
• intestinal inflammation;
• bronchial asthma;
• individual sensitivity to the components of the drug.

Also, with caution and only under the supervision of a physician, drugs can be used in patients with diabetes mellitus, fluid retention and edema.

The dosage depends on the patient's condition, concomitant diseases, age. In any case, the duration of treatment should not exceed 5 days, and the daily dose should not exceed 60-90 mg.

Common side effects from taking NSAIDs include:

• diarrhea, constipation, heartburn, nausea, acute pancreatitis, hepatitis;
• nephritis, acute renal failure, edema, frequent urination;
• allergic rhinitis, laryngeal edema, shortness of breath;
• headache, dizziness, hearing loss, visual disturbances, drowsiness, depression;
• fainting;
• anemia, blood clotting;
• rash and peeling of the skin, other skin manifestations;
• allergic reactions;
• increased sweating, weight gain.

Also, anti-inflammatory drugs include Chondroitin sulfate and drugs with the same active ingredient - Artradol, Chondrolon, Honlrogard, Mukosat. However, these drugs also have a chondroprotective effect, that is, they contribute to the restoration of cartilage tissue. They are prescribed in the event that back pain is caused by diseases of the spine, accompanied by the destruction of cartilage.

Quite often, back pain is caused by muscle spasm, which must be removed as soon as possible in order to alleviate the patient's condition. With muscle spasm, a secondary radicular syndrome also occurs. For pain relief in this case, it is advisable to use muscle relaxants:

• Tolperisone;
• Mydocalm;
• Baclofen;
• Hydroxyzine;
• Tizanidine;
• Sirdalud.

If necessary, to eliminate back pain caused by diseases of the spine, accompanied by degenerative-dystrophic disorders, chondroprotectors are prescribed. The main indications for the use of chondroprotectors: polyosteoarthrosis and osteochondrosis.

Solutions for injection are administered intra-articular or deep intramuscularly. Usually the course of treatment is quite long, may include several periods of injection and breaks. As a rule, chondroprotectors do not give a quick effect, but with proper and sufficiently long treatment, they can avoid recurrences of back pain if the patient has certain diseases of the spine.

If your back hurts, you need to see a doctor for a diagnosis. Only according to its results, injections against pain can be prescribed.

Milgamma is a medical product containing B vitamins (B1, B6, B12) and lidocaine.

This multivitamin has a beneficial effect on the body with degenerative and inflammatory pathologies of the musculoskeletal system, disorders of the nervous system.

Let's look at the reviews of people who used the drug Milgamma in their treatment.

"Hello! "Milgamma" was prescribed to me along with other drugs for exacerbation of osteochondrosis. At the time I started taking the drugs, I no longer had severe pain in the neck and lower back, but my arms and legs (especially my fingers) began to go numb, then my face and lips. This made me very anxious.

The doctor prescribed 10 injections of "Milgamma" for 10 days. It took 2 packs of 5 ampoules. The first five injections seemed completely painless to me, but the subsequent ones became more and more unpleasant. I also felt the effect after five days: my arms and legs practically ceased to go numb.

I also noticed that my nails and hair became stronger. As for the hair, perhaps a change of shampoo also gave a positive effect. I didn't have any side effects. In order to prevent the development of undesirable manifestations of the action of the drug, the doctor advised to drink more water.

So, I am satisfied with the effectiveness of Milgamma. I got rid of unpleasant symptoms, I also felt a surge of energy and vitality. The price is also acceptable, not the cheapest, but not super expensive either.

“I was prescribed this drug for osteochondrosis (or a hernia, I still didn’t understand). Milgamma is generally well tolerated.

The back against the background of the use of the medication began to hurt much less, the treatment had a good effect on the hair and nails. But ... there is a huge drawback! Somewhere after 3 injections, huge and painful pimples began to appear on the face. Since my skin is not prone to this, I was very upset. She reached five injections, then stopped injecting. After a couple of days, the pimples began to disappear slowly, although very slowly. Probably, "Milgamma" is not suitable for everyone.

“I have always wondered why B vitamins are considered painful. Never had a chance to prick them before. Everything happens for the first time. I caught a cold, osteochondrosis worsened with my protrusion of the body of the eighth vertebra, myositis also developed. In general, "Milgamma" was the fourth drug in the list of medicines prescribed by the doctor.

In general, three injections and tablets were obtained. I was very worried that "Milgamma" would be very painful. I read some advice online and decided to give it a try. First, she warmed the syringe under the knee for 5 minutes, and asked her husband to administer the medicine very slowly. I did not feel any pain other than the sensation of the puncture itself. Actovegin, which was also prescribed to me, turned out to be even more painful when administered with the medicine.

I also did not notice any allergic reactions (at least cough), although I suffer from bronchial asthma and cannot tolerate many drugs.

The biggest, and the only negative for me was painful subcutaneous acne. They were sick for a very long time, did not ripen absolutely and were not dried by anything. A week later, they began to pass on their own, although they had to fight against stains from them. Then, periodically, the same subcutaneous elements appeared in the ears, and throughout the body. They went away on their own with time. Then this phenomenon stopped.

In general, the effect of Milgamma is really very good, but you need to be prepared for side effects.

“The curvature of the spinal column I have developed since my school years. I did not notice any discomfort, I think, due to active sports. However, somewhere from the age of 20, when my sports activity faded away and nutrition was already far from correct, I began to feel pain in the upper region of the spine. There were also episodes of insane pain in the right arm. But I didn't pay much attention to it. A year later, the pain became much more intense, but again I did not go anywhere.

When I was 22, I got pregnant. To my surprise, the pain was almost non-existent. I think this was the result of proper nutrition, physical activity, taking a complex of vitamins.

After the birth of my son, my lower back also began to hurt. A few months later it moved to the legs, then the arms. All the bones were in constant pain. Mom insisted on a consultation with a chiropractor. He said that there is also lordosis (excessive curvature of the spine in the lower back). The chiropractor insisted on an MRI. In general, I did not appear with him again, as it turned out in vain.

1.5 years after the birth, due to pain, the legs began to fail. I didn't even have the strength to pick up the baby. Mom insisted that I pierce myself with a course of Milgamma. I read reviews and decided on a course of the drug together with Mexidol. 10 days of treatment with these drugs practically relieved me of pain. Finally, I could sleep peacefully and walk.

About a month later, the pain returned again. But, probably, I myself am to blame for this, the cause of the disease was not treated. Also, the food again consisted mostly of sandwiches and sweet tea. There was also no gymnastics for the spine.

“I have to very often resort to the intramuscular injection of Milgamma, since I have been suffering from diseases of the musculoskeletal system for a long time. It is very effective as a pain reliever. Improves blood circulation.

After the elimination of acute attacks of pain, according to the doctor's recommendations, I replace the injections with capsules. The overall effect of "Milgamma" on the body can be assessed as restoring and invigorating the body. No side effects were observed."

“But Milgamma didn’t help me at all. On the contrary, it hurt. After a couple of days, the cramps in the arm became stronger and more frequent, became irritable, and there was a feeling of weakness.

After the 5th injection, blood began to flow from the nose in the morning. I had to stop taking this medication."

“I use courses for exacerbations of intervertebral hernia. Very helpful, I recommend. I advise you to use original drugs, not generics, as they are more effective and less likely to cause side effects.

"Great drug! I apply every six months. I suffer from arthrosis, osteochondrosis, muscle spasms of the lumbar spine. Sometimes it seems that you are about to become a paralytic ... However, after the first injection, within a day you feel like a person again.

“Kolem to our grandmother“ Milgamma ”. She has a terrible pain in her back after an injury. A traumatologist prescribed the drug 3 months after a crack in the left femur. Grandma has been smiling and sleeping peacefully for two days now. We are very grateful to the doctor for prescribing this medication.

Victoria

“Musculoskeletal and neurological disorders are quite common in people of various age categories. Injections and tablets of the drug "Milgamma" are somewhat different in their action. Injections with slow and correct administration of the drug are painless, and the therapeutic effect occurs after a few days of treatment.

When taking the drug inside, relief comes much later. The medicine is very effective in eliminating unwanted manifestations of neurological diseases, and the effectiveness of Milgamma in the treatment of stress manifestations and herpetic infection has also been noticed.

Sometimes patients complain of allergic manifestations that disappear after a course of treatment with the drug. There are also such side effects as convulsions, arrhythmias, increased sweating, dizziness. As a rule, the side effects of the drug appear when the dosage rules are violated, the rapid administration of the drug solution.

It is not recommended to use the drug for people with hypersensitivity to the individual components of Milgamma. It is also not advised to prescribe medication to patients with disorders in the heart muscle, mothers during breastfeeding, pregnant women. It is categorically impossible to prescribe the drug to newborn children.

Vladimir, doctor

“My sister really helped with osteochondrosis. I also decided to take a course of treatment with Milgamma. A couple of days later, like many others, I developed a rash on my skin. Painful and ugly acne on the face is too much. I had to change the drug.

“I made an injection of Milgamma once. I've had enough. After the injection, there was a feeling of lack of air, severe tachycardia, several times panic attacks. So he lived until the morning, he did not inject more. It probably doesn't suit everyone. The feeling of pain has really passed, but still I won’t risk it anymore. ”

“I have had intervertebral hernia in the lumbar for many years. In 2004, due to an exacerbation of the disease, she fell ill. Have appointed or nominated nyxes of vitamins of group In courses with the prophylactic purpose twice a year. A total of 30 injections! Later, I learned about Milgamma from a friend.

I pierced the drug for 10 days for prevention. Exacerbations of the disease did not disturb for 10 years. The attending physician was amazed by my condition. Milgamma certainly helped me. And, of course, gymnastics enhanced the effect.

So, the drug "Milgamma" is quite popular for violations of the functionality of the nervous system and the musculoskeletal system. Despite the presence of both positive and negative reviews, in general, Milgamma has established itself as an effective and high-quality medicine.

The tool has the following effects:

• stimulation of the processes of restoration of tissues of the nervous system;
• antioxidant effect;
• activation of regenerative abilities of tissues;
• strengthening of metabolic processes;
• restoration of normal blood supply in the affected area;
• analgesic effect on nerve endings.

Milgamma is produced in the form of a dragee and an injection solution. According to the instructions for use, injections are prescribed in cases of acute pain, exacerbations of chronic diseases, and a serious condition of the patient.

Side effects, as a rule, occur with the rapid introduction of an injection solution, exceeding the recommended doses. This drug has a powerful systemic effect on the human body. That is why it is important to start the course of treatment with Milgamma according to the recommendations of an experienced doctor. Self-medication can lead to the development of undesirable effects and treatment failure.

The drug incorporates therapeutic doses of B vitamins. The drug is used in the medical practice of neuropathologists, orthopedists, traumatologists, rheumatologists. Vitamins of group B have a beneficial effect on the process of blood formation, optimize blood supply to the affected areas, and in high concentrations have an analgesic effect.

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The main symptom of osteochondrosis is pain. It is present in almost all stages of the disease. The intensity of the pain syndrome depends on the prevalence and degree of pathological changes in the tissues of the intervertebral discs and vertebrae, the tension of the muscle fibers, the neglect of the inflammatory process, and a number of other factors. One of the main ways to treat osteochondrosis is drug therapy. Unfortunately, not all of the prescribed funds are highly effective. The action of local preparations (ointments, gels) mainly leads to a limited local effect, and many of the oral drugs do not affect the cause and cannot eliminate the inflammatory process. In the treatment of osteochondrosis, Mydocalm has proven itself well.

Muscle spasm compresses blood vessels

What is the danger of muscle spasm? In addition to provoking pain, contraction of muscle fibers can lead to a number of serious consequences.

1. The main possible result of a spasm is squeezing of the blood vessels. Compression of blood vessels leads to impaired blood circulation. Such a phenomenon is especially dangerous in cervical osteochondrosis, since it results in a violation of cerebral circulation, an insufficient supply of certain parts of the brain with nutrients and oxygen. The use of Mydocalm in this form of osteochondrosis is of great importance, since it helps to prevent the development of formidable complications.
2. Another consequence of muscle spasm is the compression of nerve endings, which provokes the occurrence of severe pain of a radiating nature. In addition, the work of internal organs innervated by injured fibers may be disrupted.

Preparations of this group are used to relieve muscle tension in pathological lesions of the spine, including osteochondrosis.

Mydocalm relieves muscle tension

The best way to get rid of spastic pain is centrally acting muscle relaxants, i.e. directed directly at the parts of the central nervous system responsible for the regulation of muscle tone. Mydocalm also belongs to this group.

The results of numerous studies show that when muscle relaxants are added to the standard treatment regimen for osteochondrosis based on non-steroidal anti-inflammatory drugs, analgesics, physiotherapy and massage, it is possible to significantly increase the effectiveness of therapy, achieve relief or reduction of pain in a short time and increase the mobility of the damaged spinal column.

The use of Mydocalm in osteochondrosis has a number of obvious advantages:

Tablets Mydocalm

• The central muscle relaxant effect it has is highly selective. The drug reduces the degree of excitability of muscle fibers, but it does not have an overwhelming effect on nerve impulses, due to which the necessary muscle strength is provided during movement and correct posture is maintained.
• Even with prolonged use, Mydocalm is well tolerated and does not lead to dangerous side effects.
• Treatment with this muscle relaxant does not affect the patient's activity, does not reduce his physical and mental capacity for work.
• Mydocalm fits perfectly into the traditional scheme for the treatment of osteochondrosis of the cervical, thoracic or lumbar regions and is combined with other used drugs.
• Due to the pronounced muscle relaxant and analgesic effect provided by the drug, it is possible to reduce the dosage of non-steroidal anti-inflammatory drugs. As a result, their negative side effect on the internal organs is eliminated, while the effectiveness of the treatment of osteochondrosis is not reduced at all.

Currently, Mydocalm is considered the most effective and safe of the existing muscle relaxants. It has been used in clinical practice for over 50 years.

Mydocalm is used to treat neurological syndromes, accompanied by pain, increased muscle tone and trophic disorders.

The active substance of the drug has a local anesthetic and membrane-stabilizing effect. With osteochondrosis and other diseases Mydocalm:

Mydocalm contains lidocaine

• helps to eliminate muscle tension;
• leads to an indirect analgesic effect;
• dilates blood vessels;
• improves blood circulation and lymph flow.

International non-proprietary name of the drug (INN) Tolperisone.

One tablet of Mydocalm contains 50 or 150 mg tolperisone hydrochloride as an active substance, as well as auxiliary components:

• citric acid monohydrate ( acidum citricum monohydrate);
• colloidal silicon dioxide ( Silicii dioxydum colloidal);
• stearic acid ( Acidum stearicum);
• talc ( Talcum);
• microcrystalline cellulose ( Cellulosum microcrystallicum);
• corn starch ( Amylum maidis);
• lactose monohydrate ( lactose monohydrate).

The film-coated tablets contain:

• colloidal silicon dioxide ( Silicii dioxydum colloidal);
• titanium dioxide ( Titanium dioxide);
• lactose monohydrate ( lactose monohydrate);
• macrogol 6000 ( Macrogol 6000);
• hypromellose ( Hypromellose).

Release form

The drug Mydocalm is available in the form of film-coated round biconvex tablets. On the one hand, each tablet has an engraving “50” or “150” (depending on the amount of active substance in it).

The color of the tablets is white or almost white (including at the break), the smell is mild, specific.

pharmachologic effect

Mydocalm belongs to the pharmacotherapeutic group centrally acting muscle relaxants and is a drug that helps reduce the tone of skeletal muscles. The mechanism of action of the drug is not fully understood.

Pharmacodynamics and pharmacokinetics

Mydocalm prevents destruction cell membranes and provides a pronounced membrane-stabilizing effect. The mechanism of this action is based on the inhibition of peroxidation processes. lipids and modulation of membrane-bound activity.

In addition, the drug acts as a local anesthetic, and also inhibits the conduction of nerve impulses in the primary afferent (from Latin “ afferens”- bringing) nerve fibers and motor neurons - nerve cells responsible for carrying information to effectors (usually muscles) from the central nervous system.

The latter leads to blocking polysynaptic and monosynaptic reflexes of the spinal cord .

It is considered likely that Mydocalm has the ability to secondarily inhibit the release of mediators. This is ensured by inhibiting the flow of calcium ions (Ca2+) to the functional contact sites between neurons in which information is transferred from one cell to another (or, in other words, to synapses).

In the brain stem, Mydocalm eliminates the facilitation of the spread of excitation along the reticulospinal tract (reticulospinal tract).

It helps to increase peripheral blood flow (regardless of the influence of the central nervous system), reduces pathologically increased muscle tone, eliminates muscle rigidity, reduces the severity of pain in the muscles, eliminates or reduces the severity of violations of voluntary active movements.

This effect is provided by the ability tolperisone provide a subtle antispasmodic and adrenoblocking action.

Thanks to activity tolperisone , Mydocalm also reduces the toxicity of the indole alkaloid, helps to suppress the increase in reflex excitability caused by it, and has vasodilating properties.

Some evidence suggests that the drug has a selective inhibitory effect on the caudal (from Latin “ cauda”- tail, caudal) part of the formation going to the thalamus in the rostral direction (that is, to the cortex) spinal cord . As a result, the severity of spastic phenomena decreases.

According to Wikipedia, which is part of Mydocalm tolperisone also causes a central N-holinolytic effect.

The action of N-anticholinergic drugs is based on the fact that, when they enter the body, they act on nicotinic receptors localized mainly in postsynaptic membranes located in skeletal muscle synapses, ganglia autonomic nervous system , tissues that form the medulla adrenal glands , as well as in tissues carotid sinus zone .

Interacting with receptors, N-anticholinergics and, in particular, tolperisone, block their ability to perceive acetylcholine , as a result of which the nerve impulse is not transmitted through the blocked synapse. Thus, the neurotransmitter is released, but the blocked receptors of the postsynaptic membrane are no longer able to respond to the stimulus.

At the same time, tolperisone does not have a pronounced effect on the peripheral parts of the nervous system.

After taking Mydocalm tablets, tolperisone is well absorbed from the gastrointestinal tract. The maximum concentration of the substance is noted after about half an hour to an hour. Its biological activity is about 20%.

Tolperisone undergoes intensive biotransformation in the tissues of the liver and kidneys. From the body, the substance is excreted by the kidneys in the form of end products (more than 99%), the pharmacological activity of which is unknown.

Indications for the use of Mydocalm, what treats and what the drug helps with

Indications for the appointment of Mydocalm are:

• pathologically increased muscle tone and spasms of skeletal (striated) muscle tissue, which are the result of organic lesions of the central nervous system, including but not limited to scattered , encephalomyelitis , brain, etc.;
• myogenic contractures, increased muscle tone and spasticity due to diseases of the musculoskeletal system (for example, with sciatica , spondylosis affecting large joints arthrosis ,cervical syndrome etc.);
• non-inflammatory diseases of the brain, accompanied by disorders of muscle tone (for example, cerebral palsy );
• cholelithiasis ;
• severe pain syndrome, observed against the background of the development of hemorrhoids;
• menstrual pain syndrome;
• the threat of spontaneous interruption due to an increase in the tone of the uterine muscle structures;
• renal colic .

The use of the drug Mydocalm is indicated:

• during the period of rehabilitation therapy after orthopedic, surgical or traumatological operations (this is due to the ability tolperisone have a beneficial effect on the degree of stretching of muscle fibers);
• as part of complex therapy for obliterating vascular lesions (according to the annotation, the remedy is effective in diabetic angiopathy , thromboangiitis obliterans etc.);
• for symptomatic treatment muscle spasm in adult patients who have undergone;
• with pathologies caused by disorders of vascular innervation (gross gait disturbances or pathological cyanosis of the extremities).

Why are muscle relaxants prescribed for osteochondrosis?

Like other centrally acting muscle relaxants, Mydocalm can be prescribed for.

The pain syndrome that develops with osteochondrosis provokes a compensatory spasm of the deep layers of the back muscles. And this, in turn, causes myopically fixation of the spinal column and limitation of mobility of the spinal motion segments.

The consequence of such a muscular-tonic imbalance is a deterioration in the course of the disease and a decrease in the therapeutic effectiveness of all measures taken.

Muscle relaxants for osteochondrosis are prescribed in order to eliminate this imbalance. Drugs from this pharmacotherapeutic group:

• have a sedative effect;
• relieve symptoms of pain syndrome;
• suppress spinal reflexes;
• relieve muscle tension.

Due to these qualities, muscle relaxants increase the effectiveness of other therapeutic measures: massage, exercise therapy, traction therapy, etc. They also have the ability to potentiate the effect of blockades, other painkillers and physiotherapy procedures.

At the same time, muscle relaxants have a number of contraindications for prescription and can provoke undesirable side effects (in particular, with long-term treatment with them, patients often have impaired function). hepatobiliary system and weight gain).

However, unlike drugs chondroprotectors , they really improve the condition of patients suffering from osteochondrosis (which is ensured by removing pathological myopically), and increase the effectiveness of conservative therapy.

For treatment osteochondrosis taking muscle relaxants is recommended for very short courses. And yet, mindful of the abundance of side effects, practitioners are very careful to include these drugs in the treatment regimens of their patients.

Contraindications

Contraindications to the appointment of Mydocalm tablets:

• age up to one year;
• persistent pathological weakness and rapid fatigue of skeletal muscle tissue ();
• increased individual sensitivity to any of the components of the drug.

Before taking Mydocalm tablets with osteochondrosis , it should also be noted that all muscle relaxants are contraindicated in patients:

• who currently have or have a history of increased seizure activity;
• suffering from ;
• suffering from chronic renal and/or liver failure ;
• suffering from;
• having a history of drug addiction;
• having a history acute psychoses .

Side effects of Mydocalm

Safety profile of tablets containing tolperisone , based on data from over 12,000 patients.

Statistics show that most often after taking tolperisone preparations there were such adverse reactions as systemic disorders, disorders of the skin and subcutaneous tissue, as well as nervous disorders and digestive disorders.

Post-marketing observations have shown that in 50-60% of cases, the side effects associated with taking tolperisone preparations are individual hypersensitivity reactions.

Most of these reactions do not threaten the patient's health, do not require the appointment of specific treatment and go away on their own.

Life-threatening hypersensitivity reactions were recorded in isolated cases.

In accordance with the Medical Dictionary of Regulatory Activity MedDRA All side effects that occur during treatment with a particular drug are classified into frequent, infrequent, rare and very rare.

Infrequent (occur no more than once in a thousand cases) side effects that are noted after taking Mydocalm include:

• nutritional and metabolic disorders, which are expressed in the form anorexia ;
• , elevated ;
• arterial hypotension ;
• feeling of discomfort in the abdomen, increased dryness of the mucous membrane in the mouth, dyspeptic symptoms, nausea;
• muscle weakness, pain in the extremities, muscle pain;
• asthenia feeling of general discomfort, increased fatigue.

Rare adverse reactions that occur more often than once in a thousand cases, but less than once in ten thousand cases:

• anaphylactic reaction;
• decreased activity, depression;
• attention disturbances, increased seizure activity, hypoesthesia (decrease in sensitivity to stimuli), paresthesia , increased drowsiness;
• ,vertigo ;
• , palpitations, lowering blood pressure;
• hyperemia skin;
• difficulty breathing, nosebleeds, rapid breathing;
• pain in the epigastric region, , vomit;
• mild forms of dysfunction liver ;
• allergic , increased sweating, skin itching, skin rashes;
• feeling of discomfort in the limbs;
• a feeling of intoxication, a feeling of heat, irritability, increased ;
• an increase in the level of bilirubin in the blood, a change in the activity of liver enzymes, a decrease in the level, leukocytosis .

Extremely rarely (not more often than in one in ten thousand cases) can be noted:

• anemia , swollen lymph nodes ();
• (anaphylactic shock);
• polydipsia ;
• confusion of consciousness;
• bradycardia ;
• osteopenia ;
• feeling of discomfort in the chest;
• increase in blood levels.

Mydocalm tablets, instructions for use (Method and dosage regimen)

The medicine is intended for oral administration. It is optimal to take it immediately after a meal, without chewing and drinking a small amount of liquid.

Adults are advised to start treatment with the drug with a dose of 100-150 mg per day, which is divided into 2 or 3 doses. Further treatment involves a gradual increase in a single dose to 150 mg. The frequency of receptions remains unchanged (2-3 per day).

Usually the dosage is selected depending on muscle tone , intensity pain syndrome , the presence of contraindications and concomitant chronic diseases in the patient.

Based on these data, the doctor also determines how many days to take the pills. The duration of the therapeutic course usually does not exceed ten days.

According to the instructions for the use of Mydocalm, children under the age of fourteen are allowed to prescribe tablets containing 50 mg of tolperisone.

For children aged from one to six years, the drug Mydocalm is given at a dose equal to 5 mg of tolperisone per kilogram of the child's body weight per day. The indicated dose during the day is divided into 3 doses. In cases where the child is not able to swallow the whole tablet, it is pre-rubbed.

For children from seven to fourteen years of age, the instruction for the use of Mydocalm recommends prescribing the drug in a daily dose equal to 2 to 4 mg of tolperisone per kilogram of the child's body weight. The multiplicity of receptions is 3.

After oral administration, the drug begins to act after about forty minutes. The duration of action varies from 4 to 6 hours (it depends on how well the renal blood filtration system functions).

The treatment of certain diseases is supplemented with a complex of physiotherapeutic measures, gymnastics, massage courses, rubbing ointments, etc.

Overdose

There are no data on overdose with Mydocalm. The drug is characterized as non-toxic and has a wide range of therapeutic effects. In the literature, there are descriptions of oral administration in pediatric patients of a dose of tolperisone equal to 600 mg. And without any serious toxic manifestations.

Oral intake by children of a dose equal to 300-600 mg, in some cases, may be accompanied by an increase in irritability.

The drug has no specific antidote. If the dose recommended by the instruction is exceeded and any undesirable symptoms appear against this background, the patient is recommended gastric lavage and then symptomatic and supportive therapy.

Interaction

There are no data on interactions with other drugs that would limit the use of Mydocalm.

Despite the fact that tolperisone has the ability to act on the central nervous system, it does not provoke a sedative effect. For this reason, it is allowed to combine it with sedatives, sleeping pills and drugs containing alcohol.

Tolperisone does not affect the effect of alcohol on the central nervous system. The activity of the substance is enhanced:

• preparations for general anesthesia;
• muscle relaxants of peripheral action;
• psychotropic drugs ;
• (substance with antihypertensive effect).

Movalis, Mydocalm and Milgamma (drug compatibility)

And Mydocalm are well combined drugs. Therefore, they are often prescribed as part of complex therapy for patients with pathologies of the musculoskeletal system.

Patients with this kind of diseases in the vast majority of cases suffer from severe pain in the joints. The use of Movalis and Mydocalm together can reduce the severity of pain, relieve spasm and muscle hypertonicity. In addition, Movalis is characterized by a neutral effect on cartilage tissue.

The drug Milgamma belongs to the pharmacological group and is used as a general tonic. It has a pronounced metabolic, analgesic and neuroprotective effect.

Belonging to group B, neurotropics have a beneficial effect on inflammatory and degenerative diseases that affect the nervous system and locomotor apparatus.

Reception Scheme “ Movalis-Milgamma-Mydocalm” is determined by the attending physician.

Terms of sale

The drug belongs to the prescription category.

Storage conditions

The optimum temperature regime is not higher than 30°C.

Best before date

Tablets are usable for 3 years from the date of manufacture.

special instructions

Mydocalm does not increase the risks when driving a car and performing potentially hazardous work.

Alcohol compatibility

The combination of Mydocalm and alcohol is acceptable (in particular, simultaneous administration of the drug with alcohol-containing drugs is allowed).

Mydocalm during pregnancy and lactation

Purpose of Mydocalm pregnant and breastfeeding women allowed, but only when the expected benefit to the mother outweighs the risks to her baby.

Why do Mydocalm tablets help during pregnancy?

In the first trimester, the drug is indicated for women who have a threat of spontaneous due to increased uterine muscle tone.

Mydocalm's analogs

Coincidence in the ATX code of the 4th level:

Analogues of Mydocalm are drugs that have similar pharmacological properties to it, but contain a different active substance and are characterized by a different mechanism of action.

Analogues of the drug include:

• (active substance: tizanidine );
• Miolgin (active substances: paracetamol and chlorzoxazone );
• Lexotan (active substance: bromazepam );
• and others.

The average price of analogues in the Ukrainian market varies from 65 to 140 UAH. In Russia, they can be purchased at an average of 220-380 rubles.

• average cost of a pack of tablets Sirdalud — 110 UAH/220 Russian rubles;
• average cost per pack Miolgina — 140 UAH;
• average price of tablets Baclofen 10 mg - 65 UAH / 230 Russian rubles.

Which is better: Sirdalud or Mydocalm? Baclofen or Mydocalm?

There is no single answer to this question, since each of the drugs has its own advantages.

If we compare Mydocalm with Sirdalud, then both drugs belong to the same pharmacotherapeutic group, but they contain different substances as an active ingredient. Mydocalm was released to the pharmaceutical market a little earlier and therefore has been studied better than its counterpart.

Mydocalm is characterized by a wider spectrum of action, but, unlike it, Sirdalud provokes fewer unwanted side reactions.

Back pain and their treatment with Mydocalm

Professor V.A. Parfenov
MMA named after I.M. Sechenov
T.T. Batysheva
Rehabilitation Clinic No. 7, Moscow

Backache, or dorsalgia, can be a symptom of various diseases. Backache- one of the most frequent complaints in general medical practice.
Main reasons back pain.
Back pain most often caused by osteochondrosis of the spine - a degenerative lesion of the cartilage of the intervertebral disc and reactive changes in the bodies of adjacent vertebrae. Damage to the intervertebral disc occurs as a result of its repeated injuries (weight lifting, excessive static and dynamic load, falls, etc.) and age-related degenerative changes. The nucleus pulposus, the central part of the disc, dries out and partially loses its shock-absorbing function. The fibrous ring, located along the periphery of the disc, becomes thinner, cracks form in it, to which the nucleus pulposus is displaced, forming a protrusion (prolapse), and when the fibrous ring is ruptured, a hernia. In the affected vertebral segment, relative instability of the spine occurs, osteophytes of the vertebral bodies develop (spondylosis), ligaments and intervertebral joints are damaged (spondylarthrosis). Hernias of the intervertebral discs most often occur in the lower lumbar discs, less often in the lower cervical and upper lumbar, extremely rarely in the chest. Disc herniations in the vertebral body (Schmorl's hernias) are not clinically significant, disc herniations in the posterior and posterolateral directions can cause compression of the spinal root (radiculopathy), dorsal brain (myelopathy at the cervical level) or their vessels. In addition to compression syndromes, reflex (muscle-tonic) syndromes are possible, which are caused by impulses from receptors in response to changes in the discs, ligaments and joints of the spine.
Reflex syndromes of osteochondrosis of the spine occur during the life of almost every person, compression develop much less frequently. The reflex muscle tension initially has a protective character, since it leads to the immobilization of the affected segment, but later becomes a factor supporting pain.
Another common reason back pain and limbs - myofascial pain caused by the formation of so-called trigger zones in the muscles and / or associated fascia. Trigger zones occur under the influence of muscle tension and often against the background of osteochondrosis of the spine. When exposed to them - stretching, compression, palpation - occurs pain that determines the diagnosis.
Backache may be the only symptom of a tumor dorsal brain, syringomyelia and other diseases dorsal brain. It occurs with the destruction of the vertebrae and damage to the nerve roots due to infectious processes (tuberculous spondylitis, spinal epidural abscess), with neoplasms (primary and metastatic tumors of the spine, multiple myeloma), dysmetabolic disorders (osteoporosis, hyperparathyroidism, Paget's disease). Backache may be the result of a fracture of the spine, its congenital or acquired deformities (scoliosis and others), stenosis of the spinal canal, displacement of the vertebral bodies (spondylolisthesis), ankylosing spondylitis.
Backache possible with various somatic diseases (heart, stomach, pancreas, kidneys, pelvic organs, etc.) according to the mechanism of reflected pain.
Examination and diagnosis back pain
Any back pain attributed to "osteochondrosis" - a condition that is detected by X-ray examination in most middle-aged and elderly people.
To establish the cause back pain a thorough examination of the patient is necessary, including clarification of complaints, history taking, somatic and neurological examination, as well as additional studies.
When collecting complaints and anamnesis, it is necessary to find out:
- localization and irradiation of pain;
- dependence of pain on the position of the body and movement in the spine;
- previous injuries and diseases (malignant neoplasms and others);
- emotional state, reasons for simulation or aggravation.
Somatic examination is aimed at identifying malignant neoplasms, infectious processes and somatic diseases that may manifest themselves. back pain. During a neurological examination, it is necessary to assess the emotional state of the patient, determine whether there are paresis, sensitivity disorders, loss of reflexes, examine the mobility of the spine, range of motion of the limbs, determine local pain in back and leg.
Additional research:
1) X-ray of the spine in several projections,
2) general blood test,
3) biochemical blood test (calcium, creatinine, phosphates, glucose, etc.),
4) if indicated - computed x-ray tomography (CT) or magnetic resonance imaging (MRI) of the spine.
The diagnosis of reflex and compression complications of osteochondrosis is based on clinical data.
Lumbago (lumbar backache) is characterized by a sharp, shooting pain in the lower back, which usually develops during physical exertion (lifting weights, etc.) or awkward movement. The patient often freezes in an uncomfortable position, an attempt to move leads to increased pain. Examination reveals muscular-tonic syndrome: muscle tension back, usually scoliosis, flattening of the lumbar lordosis, a sharp limitation of mobility in the lumbar spine. For lumbodynia ( backache) and lumboischialgia ( backache and along the back of the leg) are characterized by pain that occurs after physical exertion, awkward movement or hypothermia. The pains are aching in nature, aggravated by movements in the spine, certain postures, walking. Examination reveals muscular-tonic syndrome without paresis, sensitivity disorders and loss of reflexes.
Radiculopathy of the lumbar and first sacral roots is manifested by acute shooting pain in the lower back and leg. When examining a patient, in addition to the muscular-tonic syndrome, sensitive, reflex and less often motor disorders are detected in the area of ​​the affected root. The fifth lumbar (L5) and first sacral (S1) roots are more commonly affected, less frequently the fourth lumbar root, and very rarely the upper lumbar roots.
Cervicalgia (pain in the neck) and cervicobrachialgia (pain in the neck and arm) are characterized by pain that occurs after exercise or awkward movement of the neck. There is an increase in pain during movements in the neck or, conversely, with a long monotonous position (in a car or on an airplane, after sleeping on a dense high pillow, etc.). During the examination, a muscular-tonic syndrome is revealed: tension of the neck muscles, restriction of movements in the cervical region. Radiculopathy of the lower cervical roots are much less common than reflex syndromes, and manifest themselves, in addition to the muscular-tonic syndrome, with sensory, reflex and / or motor disorders in the zone of innervation of the affected root.
In the thoracic region, reflex and compression syndromes of osteochondrosis are much less common than in the lumbar and cervical regions. They show up back pain, violation of sensitivity in the area of ​​the affected roots.
X-ray of the spine is used mainly to exclude congenital anomalies and deformities, inflammatory diseases (spondylitis), primary and metastatic tumors. X-ray CT or MRI can identify a herniated disc, determine its size and location, and detect spinal stenosis.
The diagnosis of myofascial pain is based on clinical findings and requires the exclusion of other possible causes of pain. Myofascial pain is manifested by muscle tension and the presence of trigger points in them, the identification of which is carried out by manual examination of the muscles. An active trigger point is a constant source of pain, aggravated by its palpation in the muscle; latent trigger point pain only on palpation. For each muscle, there is an independent myofascial syndrome, with a characteristic localization of pain upon stimulation of the trigger zone, extending beyond the projection of the muscle onto the skin surface. There are no symptoms of damage to the peripheral nervous system, except for those cases when tense muscles compress the nerve trunk. In the absence of supporting factors, myofascial pain may resolve spontaneously if the muscle is allowed to rest for a few days.
With a tumor dorsal brain, syringomyelia and other diseases of the spinal cord backache often combined with other neurological disorders, usually there is no musculo-tonic syndrome. Diagnosis is by CT or MRI of the spine.
With a destructive lesion of the spine (tuberculous spondylitis, primary tumor or metastasis to the spine, osteoporosis, hyperparathyroidism), fracture of the spine, its congenital or acquired deformities, deforming spondyloarthritis, local pain is often observed, the diagnosis is established on the basis of the results of radiographs and / or CT or MRI of the spine.
In somatic diseases reflected backache usually combined with other manifestations of the disease, it is not accompanied by muscle tension back and usually does not increase with movements in the spine.
Back pain treatment
Back pain treatment based on the treatment of the underlying disease. Below we will talk about treatment with the most common causes back pain- reflex and compression complications of osteochondrosis and myofascial pains.
Treatment reflex syndromes and radiculopathy due to osteochondrosis is based in the acute period on rest, avoidance of sharp bends and painful postures. In the acute period, it is better to treat at home, without forcing the patient to visit the clinic for injections or physiotherapy, the benefits of which are much less than the harm associated with a high probability of increasing pain due to premature overactivation. Recommend bed rest for several days until the sharp pain subsides, a hard bed (shield under the mattress), taking analgesics, non-steroidal anti-inflammatory drugs and muscle relaxants. If you need to move, you should wear a cervical or lumbar corset (fixing belt). You can use physiotherapeutic analgesic procedures, rubbing in ointments, compresses with a 30-50% solution of dimexide and novocaine, novocaine and hydrocortisone blockades. When weakened pain recommend a gradual increase in motor activity, muscle strengthening exercises.
In the chronic course of reflex syndromes and radiculopathies, physiotherapy can be effective. treatment, non-steroidal anti-inflammatory drugs and muscle relaxants, manual therapy, reflexology, spa treatment.
Surgical treatment(removal of a herniated disc) is necessary in those rare cases when compression occurs dorsal brain or roots of the cauda equina. Surgical treatment also indicated for discogenic radiculopathy, accompanied by severe paresis, and with prolonged (more than 3-4 months) lack of effect from conservative treatment and a large disc herniation.
As a prevention of exacerbations of osteochondrosis, it is recommended to avoid provoking factors (lifting large loads, carrying a heavy bag in one hand, hypothermia, etc.) and regularly exercise medical gymnastics.
With myofascial pain it is necessary to give the muscle rest for several days. As treatment you can use muscle stretching exercises (postisometric relaxation), taking muscle relaxants, physiotherapy, reflexology or local injection of anesthetics into trigger zones, compresses with dimexide and anesthetics.
Application Mydokalma with dorsalgia
Mydocalm is a centrally acting muscle relaxant that has been widely used for 30 years in treatment reflex and compression complications of degenerative-dystrophic changes in the spine (osteochondrosis, spondylosis, spondylarthrosis) and myofascial pain.
The tonic muscle tension that occurs in these conditions can not only cause pain in itself, but also cause deformation and limitation of mobility of the spine, as well as compression of the nerve trunks and vessels passing near. For treatment these conditions, in addition to non-steroidal anti-inflammatory drugs, analgesics, physiotherapy and medical gymnastics, the use of muscle relaxants is theoretically justified, which are able to break the vicious circle of pain syndrome caused by muscle tension back and limbs.
Efficiency and safety of use Mydokalma with pain muscular-tonic syndrome of predominantly vertebrogenic origin was evaluated in 110 patients aged 20 to 75 years in a double-blind placebo-controlled study (3). In eight study centers, patients were randomized to receive Mydocalm at a dose of 300 mg per day or placebo in combination with physiotherapy and rehabilitation for 21 days.
Patients with prolonged (more than 3 months) pain syndrome predominated in both groups. There were no differences in the groups of patients according to the intake treatment and physiotherapy. 10 patients in the group treated Mydocalm, and 9 patients in the placebo group used non-steroidal anti-inflammatory drugs. Used as physiotherapy medical gymnastics, massage, hydrotherapy, electrotherapy and other procedures that were maximally standardized in both groups.
results treatment evaluated on days 4, 7, 10 and 21 treatment I am. As the main performance criterion treatment Pain pressure threshold was chosen, measured using a special device (Pressure Tolerance Meter) at 16 symmetrical points of the trunk and limbs. Patients subjectively assessed their condition according to the intensity pain, a feeling of muscle tension and mobility of the spine in 4 degrees of severity: none, slight, moderate and severe. The physiotherapist also assessed muscle tension, spinal mobility in 4 degrees of severity: none, slight, moderate and severe. In the end treatment the investigator and the patient gave an overall assessment of the efficacy and tolerability of the drug. Before the beginning treatment and upon its completion, a detailed clinical and laboratory examination was carried out, including ECG, blood pressure measurement, biochemical blood analysis for 16 indicators.
The results of the study showed that the use Mydokalma significantly more than placebo, reduces painful muscle spasm, measured objectively with a special device. Difference between groups treatment and placebo noted as early as day 4, it gradually increased and became statistically significant on days 10 and 21 of treatment, which were selected as endpoints for evidence-based comparison. These days, a positive effect was noted in most patients and to a certain extent caused by concomitant physiotherapy, however, as the results of the comparison show, it was significantly higher in the active treatment group, which confirms the effectiveness Mydokalma as a means treatment pain muscular-tonic syndromes.
Analysis of the subjective evaluation of the results treatment, given by patients after its completion (after 21 days), showed that in the group of patients who received Mydocalm, a very good estimate was significantly more common treatment. Lack of efficacy, in contrast, was significantly more common among patients in the placebo group. In general, by the end of treatment, the overall assessment of efficacy was significantly higher in the group receiving Mydocalm than in the placebo group.
Analysis of the subjective assessment of the results of treatment given by patients after its completion (after 21 days) showed no significant differences in the tolerability of Mydocalm and placebo. The vast majority of patients were well tolerated. Mydokalma. During the entire study period, 4 patients from the placebo group and only 3 patients from the Mydocalm group stopped treatment.
ECG, biochemical and hematological parameters also did not differ in the group of patients who took Mydocalm, and the placebo group.
Thus, the results of a double-blind, placebo-controlled study indicate the efficacy and safety of using Mydocalm at a dose of 300 mg per day for painful muscular-tonic syndromes. It is important to note that more than half (62%) of the patients included in the study received other therapies prior to the start of the study, and the majority of them (68%) did not improve. This indicates the effectiveness Mydokalma v treatment pain muscular-tonic syndromes resistant to therapy.
In a number of other studies, it was also noted that with vertebrogenic muscular-tonic syndrome, adding to standard therapy (non-steroidal anti-inflammatory drugs, analgesics, physiotherapy, therapeutic exercises) Mydokalma at a dose of 150-450 mg / day leads to a more rapid regression pain, muscle tension and improved mobility of the spine, without being accompanied by any side effects. In one of these studies, it was shown that with pain vertebrogenic syndrome, intramuscular administration of 100 mg of Mydocalm reduces pain after 1.5 hours, and Mydocalm treatment within a week, 200 mg / day / m, and then for 2 weeks, 450 mg / day orally has a significant advantage over standard therapy. Wherein Mydocalm treatment not only reduces pain, but also relieves anxiety, increases mental performance and is accompanied by an improvement in the functional state of the peripheral nervous system according to electroneuromyography.
With vertebrogenic muscular-tonic syndromes, the advantages Mydokalma In addition to an effective muscle relaxant and analgesic effect, there are no side effects and good interaction with non-steroidal anti-inflammatory drugs, which in many cases allows you to reduce the dose of the latter and, as a result, weaken or even completely eliminate their side effects without reducing effectiveness. treatment.
An important advantage Mydokalma before other muscle relaxants is the lack of sedation and muscle weakness when taking it. This benefit has recently been rigorously proven in a double-blind, placebo-controlled study. The study included 72 healthy volunteers (36 men and 36 women) aged 19 to 27 years (mean age 21.7 years). It lasted for 8 days, during which the volunteers randomly received 150 or 450 mg of Mydocalm per day in three doses or placebo also in three doses. Neuropsychological studies were carried out in the morning on the first and last (eighth) days of the study before, 1.5 hours, 4 hours and 6 hours after taking Mydokalma or placebo. They included the study of the speed of a simple reaction, psychomotor coordination (eye, hand and foot movements), the study of Welzel color scales.
The results of the study did not show any significant differences in reaction rates before, 1.5 hours, 4 hours and 6 hours after ingestion. Mydokalma at a dose of 50 or 150 mg or placebo. Comparison of the reaction rates before the start of the study and on the 8th day also did not show significant differences. The results of changes in the reaction rate in the group taking Mydocalm at the maximum dose of 450 mg/day and the placebo group were the same.
The results of the study show that the reception Mydokalma in a daily dose of both 150 mg and 450 mg does not cause any sedative effect in comparison with placebo and slowing down the time of motor reactions. This indicates good tolerance. Mydokalma and the possibility of prescribing it in cases where the patient continues to drive a car or his other activity requires the preservation of quick reactions and attention.
Thus, the key to successful back pain treatment an accurate diagnosis of its cause is used, since dorsalgia can be a symptom of various diseases. In many cases backache caused by painful muscle spasm due to degenerative changes in the spine or myofascial syndrome. In such cases, Mydocalm is effective and safe for its treatment, which can be used in combination with various drugs, physiotherapy and medical gymnastics.

Literature:

1. Avakyan G.N., Chukanova E.I., Nikonov A.A. The use of mydocalm in the relief of vertebrogenic pain syndromes // Zhurn. nevrol. and psychiatrist. - 2000. - No. 5. - S. 26-31.
2. Diseases of the nervous system. Guide for doctors. Edited by N.N. Yakhno, D.R. Shtulman. - M., 2001, volume 1.
3. Pratzel H.G., Alken R.-G., Ramm S. Efficacy and tolerance of repeated doses of tolperisone hydrochloride in the treatment of painful reflex muscle spasm: results of a prospective placebo-controlled double-blind trial // Pain. - 1996. - Vol. 67.-P. 417-425
4. Dulin J., Kovacs L., Ramm S. et al. Evaluation of sedative effects of single and repeated doses of 50 mg and 150 mg tolperisone hydrochloride. Results of a prospective, randomized, double-blind, placebo-controlled trial // Pharmacopsychiat. - 1998. - Vol. 31. - P. 137-142.
5. Victor M., Roper A.H. // Adams and Victor "s principles of Neurology. New York. 2001

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Preparations Movalis, Mydocalm and Menovazin can often be found in recommendations for the treatment of osteochondrosis and back pain caused by other osteopathies. However, they do not belong to the same group of medicines and are not considered analogues. Each of them is used in approximately the same cases, but there are differences that should not be forgotten.

To whom and for what purpose funds are allocated

A powerful pain reliever to relieve inflammation, available in the form of injections, tablets and suppositories

Painkillers are prescribed for all diseases associated with a violation in the spine, cartilage, muscles and nerve endings. NSAIDs, muscle relaxants and analgesics are the most common drugs to eliminate pain and the consequences of pathologies that cause back discomfort.

Sometimes they are prescribed together, but in each case the dosage cannot be universal. Most often, drugs are taken separately from each other, because not all of them are designed to deal with the same symptoms.

Movalis: features, reception, indications

The drug belongs to non-steroidal anti-inflammatory drugs, is available in tablets, suppositories and suspensions. The main active ingredient is meloxicam.

Movalis has a powerful anti-inflammatory effect, relieves hyperthermia and pain. With course use, the product remains effective for up to 3-5 days.

The indications for taking the medication are:

• back pain of unknown etiology;
• arthrosis of the hip or knee joint, as well as other large cartilages in the acute stage;
• osteochondrosis with acute pain and complications on the limbs;
• rheumatoid arthritis;
• osteoarthritis, displacement of the vertebrae and the formation of osteophytes;
• polyarthritis of small joints;
• arthritis of unknown origin;
• chronic sciatica.

Movalis in injections and tablets helps well with back and lower back pain after undergoing spinal surgery. It is a powerful medicine that prevents inflammation.

Suspension is used mainly in childhood with rheumatoid arthritis. However, the drug has many contraindications that you need to familiarize yourself with before taking it.

Features of treatment with Movalis

Movalis tablets are prescribed in the absence of stomach diseases

Movalis tablets and injections have different applications. It is better to give injections only with very severe pain according to the doctor's indications.

Features of the use of tablets:

• the doctor selects a dosage of 7.5 to 15 mg per day;
• first, the maximum dose is prescribed, then the concentration of the drug is reduced;
• therapy lasts from 5-10 days, possibly a course of treatment, regulated by a doctor.

Movalis in the form of suppositories is prescribed if the tablets are forbidden to be taken due to any gastric restrictions. A 7.5 mg suppository is administered, lie down for 15 minutes. Usually taken 1 time per day.

The drug in the form of suspensions is taken at 7.5 mg 1 time per day. This is one scoop. Sometimes the dosage is increased to 2 scoops. For children, the suspension is prescribed at 0.125 mg per 1 kg of weight. For adolescents, the dose is increased to 0.25 mg.

Injections of the drug are made into the buttocks intramuscularly, it is not administered intravenously:

• injections are given at 7.5 mg or 15 mg;
• an injection is made 1 time per day, the procedure is very painful;
• the maximum dose is 15 mg;
• use with other NSAIDs is strictly prohibited;
• course of treatment - up to 3 days;
• after the course, it is possible to extend the treatment with tablets and suspension.

The simultaneous use of Movalis and Mydocalm for back pain is a method of treatment that is prescribed quite often. Medicines should be taken on different days or times of the day, it all depends on the individual recommendations of the doctor.

The use of Menovazin for pain

Solution and ointment for local anesthesia for back problems

The medicine belongs to the group of anesthetics that can freeze pain. Menovazin is used for back pain in the form of solutions and ointments. It has a local effect and complements NSAIDs, muscle relaxants and antispasmodics, but does not affect the intestines and stomach.

The composition of the drug includes "freezing" substances:

• ethanol;
• levomenthol;
• benzocaine and anestezin (one of the substances);
• novocaine or procaine.

Additionally, it has an anti-inflammatory effect, blocking nerve impulses. Levomenthol, on the contrary, has an irritating effect, increasing the effectiveness of painkillers.

When choosing between an ointment and a solution, the patient must know their features. The ointment is better applied and is considered a more innovative product. She has a much longer shelf life. There are other benefits too:

• hermetic packaging that protects the ingredients from destruction;
• exact dosage of active ingredients;
• polymer base that improves the penetration of the cream under the skin;
• long-term preservation on the skin and prolonged action - the ointment is used up to 2 times, while the solution is used up to 4.

Among the indications for the use of Menovazin are diseases of the musculoskeletal system of an initial and moderate degree, as well as early forms of arthrosis, bruises, and rehabilitation after operations. This drug is prescribed in the absence of severe pathologies, for example, with the appearance of pain in the lower back after physical exertion.

Product Application Rules

Before using Menovazin, you need to read the instructions, exclude contraindications and learn the rules of use:

• you need to apply the medicine on clean skin so that it penetrates better into the pores;
• use the drug only on the foci of inflammation, not more than 2 times a day;
• the course of treatment is 3-4 weeks, after which the drug can be addictive.

Menovazin can be used with any other drugs, except for local anesthetics (gels, creams, ointments).

Cases of overdose with Menovazin have not been identified. It can also be used to relieve pain caused by pathologies of the kidneys or ovaries. Suitable for children over 3 years of age.

Mydocalm: application features and composition

Mydocalm prevents the accumulation of potassium in the muscles, which increases spasms

The drug belongs to the group of muscle relaxants, often used to treat spastic lesions in the presence of CNS pathologies. Mydocalm is also indicated for back pain in diseases of the spine. It relaxes spasms and reduces pressure on the nerves and blood vessels.

Mydocalm refers to drugs with a central action and is included in complex therapy:

• hernia of the spine;
• osteochondrosis;
• radiculopathy;
• additionally used for muscle diseases and pathologies of the nervous system such as cerebral palsy and multiple sclerosis.

The product is available in the form of injections and tablets. Penetrating into the muscles and nerve endings, it prevents the accumulation of potassium and other substances in them that contribute to spasm. Further, it relaxes the peripheral and transverse muscles, dilates the blood vessels.

Mydocalm is also indicated for such diseases as arthrosis of large joints, rehabilitation after surgery.

The scheme of application of the drug

With osteochondrosis, Mydocalm is used with NSAIDs to relieve pain and inflammation.

Mydocalm is aimed at relaxing the muscles of the back. Due to this, normalization of blood flow is achieved, arteries expand. Mydocalm is often prescribed together with NSAIDs, including Movalis. One of the advantages of their joint use is that Mydocalm significantly reduces the dosage of anti-inflammatory drugs, since tolperisone hydrochloride, which is part of it, relieves spasms, pressure from nerves and blood vessels. This reduces pain. The injections also include lidocaine, which helps fight pain.

Often prescribe tablet forms of the drug:

• adults and children from 14 years old - 2-3 times a day, 50-150 mg;
• children under 14 years old - up to 4 mg per 1 kg;
• children from 3 to 6 - no more than 5 mg per 1 kg.

For children and adults, when taking Mydocalm, the dosage should be divided by 2-3 times. Injections of the drug are given intravenously or intramuscularly. In the first case, it is allowed to administer 1 ml once a day, in the second - 1 ml twice a day.

The most common scope of the drug is the treatment of osteochondrosis. Thanks to the drug, the patient's headaches decrease, seizures occur less often, inflammation goes away faster. Also take it for intervertebral hernia. The drug in combination with NSAIDs acts quickly and reliably. However, this is a potent product, so it is less commonly prescribed in the initial stages.

Is it possible to use Movalis, Menovazin and Mydocalm together

Menovazin ointment can be used simultaneously with Mydocalm and Movalis

Mydocalm is not able to replace Movalis or Menovazin. These are drugs with a different spectrum of action. However, Movalis refers to very "capricious" analgesics with an anti-inflammatory effect. It differs from Mydocalm and can be used together with it at certain intervals. For back pain caused by organs, Movalis may not be as effective as Mydocalm, especially in pathologies of the kidneys, ovaries, and uterus.